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5LZP

Binding of the C-terminal GQYL motif of the bacterial proteasome activator Bpa to the 20S proteasome

Functional Information from GO Data
ChainGOidnamespacecontents
00004175molecular_functionendopeptidase activity
00004298molecular_functionthreonine-type endopeptidase activity
00005515molecular_functionprotein binding
00005737cellular_componentcytoplasm
00005839cellular_componentproteasome core complex
00005886cellular_componentplasma membrane
00010498biological_processproteasomal protein catabolic process
00019773cellular_componentproteasome core complex, alpha-subunit complex
00019941biological_processmodification-dependent protein catabolic process
00030163biological_processprotein catabolic process
00030682biological_processsymbiont-mediated perturbation of host defenses
00043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
10005886cellular_componentplasma membrane
10022624cellular_componentproteasome accessory complex
10051260biological_processprotein homooligomerization
10061136biological_processregulation of proteasomal protein catabolic process
10070628molecular_functionproteasome binding
11901800biological_processpositive regulation of proteasomal protein catabolic process
20004175molecular_functionendopeptidase activity
20004298molecular_functionthreonine-type endopeptidase activity
20005515molecular_functionprotein binding
20005737cellular_componentcytoplasm
20005839cellular_componentproteasome core complex
20005886cellular_componentplasma membrane
20010498biological_processproteasomal protein catabolic process
20019773cellular_componentproteasome core complex, alpha-subunit complex
20019941biological_processmodification-dependent protein catabolic process
20030163biological_processprotein catabolic process
20030682biological_processsymbiont-mediated perturbation of host defenses
20043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
30005886cellular_componentplasma membrane
30022624cellular_componentproteasome accessory complex
30051260biological_processprotein homooligomerization
30061136biological_processregulation of proteasomal protein catabolic process
30070628molecular_functionproteasome binding
31901800biological_processpositive regulation of proteasomal protein catabolic process
40004175molecular_functionendopeptidase activity
40004298molecular_functionthreonine-type endopeptidase activity
40005515molecular_functionprotein binding
40005737cellular_componentcytoplasm
40005839cellular_componentproteasome core complex
40005886cellular_componentplasma membrane
40010498biological_processproteasomal protein catabolic process
40019773cellular_componentproteasome core complex, alpha-subunit complex
40019941biological_processmodification-dependent protein catabolic process
40030163biological_processprotein catabolic process
40030682biological_processsymbiont-mediated perturbation of host defenses
40043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
50005886cellular_componentplasma membrane
50022624cellular_componentproteasome accessory complex
50051260biological_processprotein homooligomerization
50061136biological_processregulation of proteasomal protein catabolic process
50070628molecular_functionproteasome binding
51901800biological_processpositive regulation of proteasomal protein catabolic process
60004175molecular_functionendopeptidase activity
60004298molecular_functionthreonine-type endopeptidase activity
60005515molecular_functionprotein binding
60005737cellular_componentcytoplasm
60005839cellular_componentproteasome core complex
60005886cellular_componentplasma membrane
60010498biological_processproteasomal protein catabolic process
60019773cellular_componentproteasome core complex, alpha-subunit complex
60019941biological_processmodification-dependent protein catabolic process
60030163biological_processprotein catabolic process
60030682biological_processsymbiont-mediated perturbation of host defenses
60043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
70005886cellular_componentplasma membrane
70022624cellular_componentproteasome accessory complex
70051260biological_processprotein homooligomerization
70061136biological_processregulation of proteasomal protein catabolic process
70070628molecular_functionproteasome binding
71901800biological_processpositive regulation of proteasomal protein catabolic process
80004175molecular_functionendopeptidase activity
80004298molecular_functionthreonine-type endopeptidase activity
80005515molecular_functionprotein binding
80005737cellular_componentcytoplasm
80005839cellular_componentproteasome core complex
80005886cellular_componentplasma membrane
80010498biological_processproteasomal protein catabolic process
80019773cellular_componentproteasome core complex, alpha-subunit complex
80019941biological_processmodification-dependent protein catabolic process
80030163biological_processprotein catabolic process
80030682biological_processsymbiont-mediated perturbation of host defenses
80043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0004298molecular_functionthreonine-type endopeptidase activity
A0005839cellular_componentproteasome core complex
A0010498biological_processproteasomal protein catabolic process
A0030163biological_processprotein catabolic process
B0004175molecular_functionendopeptidase activity
B0004298molecular_functionthreonine-type endopeptidase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005839cellular_componentproteasome core complex
B0005886cellular_componentplasma membrane
B0010498biological_processproteasomal protein catabolic process
B0019773cellular_componentproteasome core complex, alpha-subunit complex
B0019941biological_processmodification-dependent protein catabolic process
B0030163biological_processprotein catabolic process
B0030682biological_processsymbiont-mediated perturbation of host defenses
B0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
C0004298molecular_functionthreonine-type endopeptidase activity
C0005839cellular_componentproteasome core complex
C0010498biological_processproteasomal protein catabolic process
C0030163biological_processprotein catabolic process
D0004175molecular_functionendopeptidase activity
D0004298molecular_functionthreonine-type endopeptidase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005839cellular_componentproteasome core complex
D0005886cellular_componentplasma membrane
D0010498biological_processproteasomal protein catabolic process
D0019773cellular_componentproteasome core complex, alpha-subunit complex
D0019941biological_processmodification-dependent protein catabolic process
D0030163biological_processprotein catabolic process
D0030682biological_processsymbiont-mediated perturbation of host defenses
D0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
E0004298molecular_functionthreonine-type endopeptidase activity
E0005839cellular_componentproteasome core complex
E0010498biological_processproteasomal protein catabolic process
E0030163biological_processprotein catabolic process
F0004298molecular_functionthreonine-type endopeptidase activity
F0005839cellular_componentproteasome core complex
F0010498biological_processproteasomal protein catabolic process
F0030163biological_processprotein catabolic process
G0004298molecular_functionthreonine-type endopeptidase activity
G0005839cellular_componentproteasome core complex
G0010498biological_processproteasomal protein catabolic process
G0030163biological_processprotein catabolic process
H0004175molecular_functionendopeptidase activity
H0004298molecular_functionthreonine-type endopeptidase activity
H0005515molecular_functionprotein binding
H0005737cellular_componentcytoplasm
H0005839cellular_componentproteasome core complex
H0005886cellular_componentplasma membrane
H0010498biological_processproteasomal protein catabolic process
H0019773cellular_componentproteasome core complex, alpha-subunit complex
H0019941biological_processmodification-dependent protein catabolic process
H0030163biological_processprotein catabolic process
H0030682biological_processsymbiont-mediated perturbation of host defenses
H0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
I0004298molecular_functionthreonine-type endopeptidase activity
I0005839cellular_componentproteasome core complex
I0010498biological_processproteasomal protein catabolic process
I0030163biological_processprotein catabolic process
J0004175molecular_functionendopeptidase activity
J0004298molecular_functionthreonine-type endopeptidase activity
J0005515molecular_functionprotein binding
J0005737cellular_componentcytoplasm
J0005839cellular_componentproteasome core complex
J0005886cellular_componentplasma membrane
J0010498biological_processproteasomal protein catabolic process
J0019773cellular_componentproteasome core complex, alpha-subunit complex
J0019941biological_processmodification-dependent protein catabolic process
J0030163biological_processprotein catabolic process
J0030682biological_processsymbiont-mediated perturbation of host defenses
J0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
K0004298molecular_functionthreonine-type endopeptidase activity
K0005839cellular_componentproteasome core complex
K0010498biological_processproteasomal protein catabolic process
K0030163biological_processprotein catabolic process
L0004298molecular_functionthreonine-type endopeptidase activity
L0005839cellular_componentproteasome core complex
L0010498biological_processproteasomal protein catabolic process
L0030163biological_processprotein catabolic process
M0004175molecular_functionendopeptidase activity
M0004298molecular_functionthreonine-type endopeptidase activity
M0005515molecular_functionprotein binding
M0005737cellular_componentcytoplasm
M0005839cellular_componentproteasome core complex
M0005886cellular_componentplasma membrane
M0010498biological_processproteasomal protein catabolic process
M0019773cellular_componentproteasome core complex, alpha-subunit complex
M0019941biological_processmodification-dependent protein catabolic process
M0030163biological_processprotein catabolic process
M0030682biological_processsymbiont-mediated perturbation of host defenses
M0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
N0004298molecular_functionthreonine-type endopeptidase activity
N0005839cellular_componentproteasome core complex
N0010498biological_processproteasomal protein catabolic process
N0030163biological_processprotein catabolic process
O0004298molecular_functionthreonine-type endopeptidase activity
O0005839cellular_componentproteasome core complex
O0010498biological_processproteasomal protein catabolic process
O0030163biological_processprotein catabolic process
P0004298molecular_functionthreonine-type endopeptidase activity
P0005839cellular_componentproteasome core complex
P0010498biological_processproteasomal protein catabolic process
P0030163biological_processprotein catabolic process
Q0004175molecular_functionendopeptidase activity
Q0004298molecular_functionthreonine-type endopeptidase activity
Q0005515molecular_functionprotein binding
Q0005737cellular_componentcytoplasm
Q0005839cellular_componentproteasome core complex
Q0005886cellular_componentplasma membrane
Q0010498biological_processproteasomal protein catabolic process
Q0019773cellular_componentproteasome core complex, alpha-subunit complex
Q0019941biological_processmodification-dependent protein catabolic process
Q0030163biological_processprotein catabolic process
Q0030682biological_processsymbiont-mediated perturbation of host defenses
Q0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
R0004298molecular_functionthreonine-type endopeptidase activity
R0005839cellular_componentproteasome core complex
R0010498biological_processproteasomal protein catabolic process
R0030163biological_processprotein catabolic process
S0004175molecular_functionendopeptidase activity
S0004298molecular_functionthreonine-type endopeptidase activity
S0005515molecular_functionprotein binding
S0005737cellular_componentcytoplasm
S0005839cellular_componentproteasome core complex
S0005886cellular_componentplasma membrane
S0010498biological_processproteasomal protein catabolic process
S0019773cellular_componentproteasome core complex, alpha-subunit complex
S0019941biological_processmodification-dependent protein catabolic process
S0030163biological_processprotein catabolic process
S0030682biological_processsymbiont-mediated perturbation of host defenses
S0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
T0004298molecular_functionthreonine-type endopeptidase activity
T0005839cellular_componentproteasome core complex
T0010498biological_processproteasomal protein catabolic process
T0030163biological_processprotein catabolic process
U0004298molecular_functionthreonine-type endopeptidase activity
U0005839cellular_componentproteasome core complex
U0010498biological_processproteasomal protein catabolic process
U0030163biological_processprotein catabolic process
V0005886cellular_componentplasma membrane
V0022624cellular_componentproteasome accessory complex
V0051260biological_processprotein homooligomerization
V0061136biological_processregulation of proteasomal protein catabolic process
V0070628molecular_functionproteasome binding
V1901800biological_processpositive regulation of proteasomal protein catabolic process
W0004175molecular_functionendopeptidase activity
W0004298molecular_functionthreonine-type endopeptidase activity
W0005515molecular_functionprotein binding
W0005737cellular_componentcytoplasm
W0005839cellular_componentproteasome core complex
W0005886cellular_componentplasma membrane
W0010498biological_processproteasomal protein catabolic process
W0019773cellular_componentproteasome core complex, alpha-subunit complex
W0019941biological_processmodification-dependent protein catabolic process
W0030163biological_processprotein catabolic process
W0030682biological_processsymbiont-mediated perturbation of host defenses
W0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
X0005886cellular_componentplasma membrane
X0022624cellular_componentproteasome accessory complex
X0051260biological_processprotein homooligomerization
X0061136biological_processregulation of proteasomal protein catabolic process
X0070628molecular_functionproteasome binding
X1901800biological_processpositive regulation of proteasomal protein catabolic process
Y0004175molecular_functionendopeptidase activity
Y0004298molecular_functionthreonine-type endopeptidase activity
Y0005515molecular_functionprotein binding
Y0005737cellular_componentcytoplasm
Y0005839cellular_componentproteasome core complex
Y0005886cellular_componentplasma membrane
Y0010498biological_processproteasomal protein catabolic process
Y0019773cellular_componentproteasome core complex, alpha-subunit complex
Y0019941biological_processmodification-dependent protein catabolic process
Y0030163biological_processprotein catabolic process
Y0030682biological_processsymbiont-mediated perturbation of host defenses
Y0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Z0005886cellular_componentplasma membrane
Z0022624cellular_componentproteasome accessory complex
Z0051260biological_processprotein homooligomerization
Z0061136biological_processregulation of proteasomal protein catabolic process
Z0070628molecular_functionproteasome binding
Z1901800biological_processpositive regulation of proteasomal protein catabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues28
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"25224505","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues14
DetailsMotif: {"description":"HbYX motif","evidences":[{"source":"PubMed","id":"25469515","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

256448

PDB entries from 2026-07-15

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