5LXI
GABARAP-L1 ATG4B LIR Complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0000045 | biological_process | autophagosome assembly |
| B | 0000421 | cellular_component | autophagosome membrane |
| B | 0000423 | biological_process | mitophagy |
| B | 0005515 | molecular_function | protein binding |
| B | 0005543 | molecular_function | phospholipid binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005776 | cellular_component | autophagosome |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005829 | cellular_component | cytosol |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005874 | cellular_component | microtubule |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0005929 | cellular_component | cilium |
| B | 0006914 | biological_process | autophagy |
| B | 0006995 | biological_process | cellular response to nitrogen starvation |
| B | 0008429 | molecular_function | phosphatidylethanolamine binding |
| B | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| B | 0030957 | molecular_function | Tat protein binding |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0031625 | molecular_function | ubiquitin protein ligase binding |
| B | 0036064 | cellular_component | ciliary basal body |
| B | 0048487 | molecular_function | beta-tubulin binding |
| B | 0050811 | molecular_function | GABA receptor binding |
| B | 0061723 | biological_process | glycophagy |
| B | 0097352 | biological_process | autophagosome maturation |
| D | 0000045 | biological_process | autophagosome assembly |
| D | 0000421 | cellular_component | autophagosome membrane |
| D | 0000423 | biological_process | mitophagy |
| D | 0005515 | molecular_function | protein binding |
| D | 0005543 | molecular_function | phospholipid binding |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005776 | cellular_component | autophagosome |
| D | 0005783 | cellular_component | endoplasmic reticulum |
| D | 0005794 | cellular_component | Golgi apparatus |
| D | 0005829 | cellular_component | cytosol |
| D | 0005856 | cellular_component | cytoskeleton |
| D | 0005874 | cellular_component | microtubule |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0005929 | cellular_component | cilium |
| D | 0006914 | biological_process | autophagy |
| D | 0006995 | biological_process | cellular response to nitrogen starvation |
| D | 0008429 | molecular_function | phosphatidylethanolamine binding |
| D | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| D | 0030957 | molecular_function | Tat protein binding |
| D | 0031410 | cellular_component | cytoplasmic vesicle |
| D | 0031625 | molecular_function | ubiquitin protein ligase binding |
| D | 0036064 | cellular_component | ciliary basal body |
| D | 0048487 | molecular_function | beta-tubulin binding |
| D | 0050811 | molecular_function | GABA receptor binding |
| D | 0061723 | biological_process | glycophagy |
| D | 0097352 | biological_process | autophagosome maturation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MG D 201 |
| Chain | Residue |
| D | ASP45 |
| D | HIS69 |
| D | HOH304 |
| D | HOH317 |
| D | HOH340 |
| D | HOH343 |
| D | HOH348 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue PGE D 202 |
| Chain | Residue |
| D | ARG65 |
| D | ALA75 |
| D | LEU76 |
| D | PHE77 |
| D | PHE78 |
| D | ILE84 |
| D | THR87 |
| D | PGE203 |
| D | PGE203 |
| D | HOH323 |
| D | TYR61 |
| D | TYR61 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue PGE D 203 |
| Chain | Residue |
| D | VAL57 |
| D | TYR61 |
| D | TYR61 |
| D | ARG65 |
| D | ALA75 |
| D | PHE77 |
| D | ILE84 |
| D | PRO85 |
| D | THR87 |
| D | PGE202 |
| D | PGE202 |
| D | HOH323 |
| D | HOH339 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 204 |
| Chain | Residue |
| D | GLN59 |
| D | PHE62 |
| D | LEU63 |
| D | HOH310 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PER D 205 |
| Chain | Residue |
| B | ARG28 |
| D | TYR25 |
| D | PRO26 |
| D | ASP27 |
| D | ARG28 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue PER D 206 |
| Chain | Residue |
| B | TYR25 |
| B | PRO26 |
| B | ASP27 |
| B | ARG28 |
| D | ARG28 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 201 |
| Chain | Residue |
| B | HIS69 |
| B | ASN98 |
| B | HOH308 |
| B | HOH313 |
| B | HOH320 |
| B | HOH336 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 202 |
| Chain | Residue |
| B | ASP54 |
| B | HOH302 |
| B | HOH306 |
| B | HOH323 |
| B | HOH332 |
| C | SEP392 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 203 |
| Chain | Residue |
| B | TYR61 |
| B | TYR61 |
| B | ALA75 |
| B | PHE77 |
| B | THR87 |
| B | HOH301 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Propeptide: {"description":"Removed in mature form","featureId":"PRO_0000420208","evidences":[{"source":"PubMed","id":"20404487","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"(Microbial infection) Cleavage; by RavZ","evidences":[{"source":"PubMed","id":"23112293","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by ATG4B","evidences":[{"source":"PubMed","id":"20404487","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Lipidation: {"description":"Phosphatidylserine amidated glycine; alternate","evidences":[{"source":"PubMed","id":"33909989","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Motif: {"description":"LIR","evidences":[{"source":"PubMed","id":"28287329","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
