5LWO

Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at 100K

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0003824	molecular_function	catalytic activity
A	0009253	biological_process	peptidoglycan catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0030430	cellular_component	host cell cytoplasm
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium
A	0044659	biological_process	viral release from host cell by cytolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue RXR A 201

Chain	Residue
A	LYS83
A	CYS115
A	CYS119
A	GLN122

---

site_id	AC2
Number of Residues	2
Details	binding site for residue CL A 202

Chain	Residue
A	HIS31
A	HOH467

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CL A 203

Chain	Residue
A	ARG145
A	HOH463
A	HOH563
A	LYS124
A	THR142
A	ASN144

---

site_id	AC4
Number of Residues	11
Details	binding site for residue HED A 204

Chain	Residue
A	ASP47
A	GLY51
A	ASN53
A	THR109
A	GLY110
A	GLY113
A	PHE114
A	HOH323
A	HOH344
A	HOH424
A	HOH439

---

site_id	AC5
Number of Residues	3
Details	binding site for residue PO4 A 205

Chain	Residue
A	ARG76
A	ARG80
A	LYS85

---

site_id	AC6
Number of Residues	3
Details	binding site for residue CL A 206

Chain	Residue
A	ASN132
A	LYS135
A	HOH387

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CL A 207

Chain	Residue
A	VAL57
A	ILE58
A	HOH553
A	HOH555
A	HOH565

---

site_id	AC8
Number of Residues	5
Details	binding site for residue BME A 208

Chain	Residue
A	ILE3
A	ASN68
A	ASP72
A	HOH408
A	HOH431

---

site_id	AC9
Number of Residues	5
Details	binding site for residue K A 209

Chain	Residue
A	GLU11
A	TYR18
A	HOH358
A	HOH393
A	HOH528

---

site_id	AD1
Number of Residues	5
Details	binding site for residue K A 210

Chain	Residue
A	GLY30
A	PHE104
A	HOH335
A	HOH347
A	HOH506

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_04110","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"3382407","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7831309","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8266098","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_04110","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1892846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3382407","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7831309","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8266098","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8266098","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7831309","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	2
Details	M-CSA 921

Chain	Residue	Details
A	GLU11	proton shuttle (general acid/base)
A	ASP20	covalent catalysis

---