5LWF

Structure of a single domain camelid antibody fragment cAb-G10S in complex with the BlaP beta-lactamase from Bacillus licheniformis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030655	biological_process	beta-lactam antibiotic catabolic process
A	0046677	biological_process	response to antibiotic
B	0008800	molecular_function	beta-lactamase activity
B	0017001	biological_process	antibiotic catabolic process
B	0030655	biological_process	beta-lactam antibiotic catabolic process
B	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ACT A 401

Chain	Residue
A	ARG164
A	GLU171
A	ASN173
A	GLN178
C	TYR62

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ACT A 402

Chain	Residue
A	LYS149
A	ARG153
A	ASN161
D	TYR105

---

site_id	AC3
Number of Residues	1
Details	binding site for residue ACT C 201

Chain	Residue
C	TYR109

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ACT C 202

Chain	Residue
B	GLU158
C	PRO103
C	THR116
C	TYR117

---

site_id	AC5
Number of Residues	1
Details	binding site for residue ACT D 201

Chain	Residue
D	TYR109

---

Functional Information from PROSITE/UniProt

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FALDTGTNRTVA

Chain	Residue	Details
A	PHE47-ALA59

---

site_id	PS00146
Number of Residues	16
Details	BETA_LACTAMASE_A Beta-lactamase class-A active site. FaFASTiKaltVGVLL

Chain	Residue	Details
A	PHE66-LEU81

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Nucleophile; acyl-ester intermediate","evidences":[{"source":"UniProtKB","id":"P62593","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P62593","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P62593","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

---