5LUX

Homeobox transcription factor CDX1 bound to methylated DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
K	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
K	0003677	molecular_function	DNA binding
K	0006355	biological_process	regulation of DNA-templated transcription
L	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
L	0003677	molecular_function	DNA binding
L	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. LAanLgLTerQVKIWFqNrrakeR

Chain	Residue	Details
K	LEU187-ARG210

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	118
Details	DNA binding: {"description":"Homeobox","evidences":[{"source":"PROSITE-ProRule","id":"PRU00108","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	42
Details	Region: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"28473536","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	22
Details	Region: {"description":"Interaction with 5-mCpG DNA","evidences":[{"source":"PubMed","id":"28473536","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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