5LUP

Structures of DHBN domain of human BLM helicase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0006260	biological_process	DNA replication
A	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
B	0003677	molecular_function	DNA binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0006260	biological_process	DNA replication
B	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
C	0003677	molecular_function	DNA binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0006260	biological_process	DNA replication
C	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
D	0003677	molecular_function	DNA binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0006260	biological_process	DNA replication
D	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
E	0003677	molecular_function	DNA binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0006260	biological_process	DNA replication
E	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
F	0003677	molecular_function	DNA binding
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0006260	biological_process	DNA replication
F	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
G	0003677	molecular_function	DNA binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0006260	biological_process	DNA replication
G	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
H	0003677	molecular_function	DNA binding
H	0005524	molecular_function	ATP binding
H	0005634	cellular_component	nucleus
H	0006260	biological_process	DNA replication
H	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
I	0003677	molecular_function	DNA binding
I	0005524	molecular_function	ATP binding
I	0005634	cellular_component	nucleus
I	0006260	biological_process	DNA replication
I	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
J	0003677	molecular_function	DNA binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0006260	biological_process	DNA replication
J	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
K	0003677	molecular_function	DNA binding
K	0005524	molecular_function	ATP binding
K	0005634	cellular_component	nucleus
K	0006260	biological_process	DNA replication
K	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
L	0003677	molecular_function	DNA binding
L	0005524	molecular_function	ATP binding
L	0005634	cellular_component	nucleus
L	0006260	biological_process	DNA replication
L	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue PO4 A 501

Chain	Residue
A	GLN365
F	GLU377
F	HOH503

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site_id	AC2
Number of Residues	2
Details	binding site for residue K B 501

Chain	Residue
B	LEU401
B	ARG404

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site_id	AC3
Number of Residues	3
Details	binding site for residue K D 501

Chain	Residue
D	ILE383
D	ILE386
D	ARG404

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site_id	AC4
Number of Residues	6
Details	binding site for residue PO4 J 501

Chain	Residue
I	HOH507
J	LEU410
J	THR412
J	HOH604
J	HOH608
I	LEU368

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	156
Details	Region: {"description":"Necessary for dimerization and homooligomerization","evidences":[{"source":"PubMed","id":"28228481","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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