5LTZ
GmhA_mutant Q175E
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008968 | molecular_function | D-sedoheptulose 7-phosphate isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0045227 | biological_process | capsule polysaccharide biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097367 | molecular_function | carbohydrate derivative binding |
| A | 1901135 | biological_process | carbohydrate derivative metabolic process |
| A | 2001061 | biological_process | D-glycero-D-manno-heptose 7-phosphate biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008968 | molecular_function | D-sedoheptulose 7-phosphate isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0045227 | biological_process | capsule polysaccharide biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0097367 | molecular_function | carbohydrate derivative binding |
| B | 1901135 | biological_process | carbohydrate derivative metabolic process |
| B | 2001061 | biological_process | D-glycero-D-manno-heptose 7-phosphate biosynthetic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0008968 | molecular_function | D-sedoheptulose 7-phosphate isomerase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0045227 | biological_process | capsule polysaccharide biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0097367 | molecular_function | carbohydrate derivative binding |
| C | 1901135 | biological_process | carbohydrate derivative metabolic process |
| C | 2001061 | biological_process | D-glycero-D-manno-heptose 7-phosphate biosynthetic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0008968 | molecular_function | D-sedoheptulose 7-phosphate isomerase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0045227 | biological_process | capsule polysaccharide biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0097367 | molecular_function | carbohydrate derivative binding |
| D | 1901135 | biological_process | carbohydrate derivative metabolic process |
| D | 2001061 | biological_process | D-glycero-D-manno-heptose 7-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue PG4 A 201 |
| Chain | Residue |
| A | ARG28 |
| A | ALA31 |
| A | THR32 |
| A | LYS35 |
| A | LEU162 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 202 |
| Chain | Residue |
| A | I22205 |
| A | HIS64 |
| A | GLU68 |
| A | HIS183 |
| D | GLU175 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue I22 A 203 |
| Chain | Residue |
| A | ASN55 |
| A | GLY56 |
| A | GLY57 |
| A | SER123 |
| A | THR124 |
| A | SER125 |
| A | SER128 |
| A | THR171 |
| A | GLU175 |
| A | HOH319 |
| A | HOH324 |
| A | HOH326 |
| B | ASN97 |
| B | ASP98 |
| D | HIS64 |
| D | GLU68 |
| D | ARG72 |
| D | PHE73 |
| A | ZN204 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue PG4 B 201 |
| Chain | Residue |
| B | GLN110 |
| D | GLU15 |
| D | ASP170 |
| D | NA203 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 202 |
| Chain | Residue |
| B | LYS35 |
| B | LEU162 |
| B | HOH310 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 203 |
| Chain | Residue |
| B | HIS64 |
| B | GLU68 |
| B | HIS183 |
| C | GLU175 |
| B | I22206 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue I22 B 204 |
| Chain | Residue |
| A | ASN97 |
| A | ASP98 |
| B | ASN55 |
| B | GLY56 |
| B | GLY57 |
| B | SER123 |
| B | THR124 |
| B | SER125 |
| B | SER128 |
| B | GLU175 |
| B | HOH305 |
| B | HOH307 |
| B | HOH325 |
| C | HIS64 |
| C | GLU68 |
| C | PHE73 |
| C | HIS183 |
| B | ZN205 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue PGE C 201 |
| Chain | Residue |
| C | ALA31 |
| C | THR32 |
| C | LYS35 |
| C | LEU162 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 205 |
| Chain | Residue |
| B | GLU175 |
| B | I22204 |
| C | HIS64 |
| C | GLU68 |
| C | HIS183 |
| site_id | AD1 |
| Number of Residues | 19 |
| Details | binding site for residue I22 B 206 |
| Chain | Residue |
| B | HIS64 |
| B | GLU68 |
| B | PHE73 |
| B | ZN203 |
| B | HOH313 |
| C | ASN55 |
| C | GLY56 |
| C | GLY57 |
| C | SER123 |
| C | THR124 |
| C | SER125 |
| C | SER128 |
| C | THR171 |
| C | GLU175 |
| B | HOH303 |
| C | HOH318 |
| B | HOH333 |
| D | ASN97 |
| D | ASP98 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue PEG D 201 |
| Chain | Residue |
| D | ALA31 |
| D | THR32 |
| D | LYS35 |
| D | LEU162 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 202 |
| Chain | Residue |
| C | GLN46 |
| C | HOH306 |
| D | ASP98 |
| D | HOH308 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue NA D 203 |
| Chain | Residue |
| B | PG4201 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 204 |
| Chain | Residue |
| D | GLU68 |
| D | HIS183 |
| A | GLU175 |
| A | I22203 |
| D | HIS64 |
| site_id | AD6 |
| Number of Residues | 18 |
| Details | binding site for residue I22 A 205 |
| Chain | Residue |
| A | HIS64 |
| A | GLU68 |
| A | ZN202 |
| C | ASN97 |
| C | ASP98 |
| D | ASN55 |
| D | GLY56 |
| D | GLY57 |
| D | SER123 |
| D | THR124 |
| D | SER125 |
| D | SER128 |
| D | THR171 |
| D | GLU175 |
| D | LYS196 |
| D | HOH316 |
| D | HOH326 |
| A | HOH333 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | ASN97 | |
| B | SER123 | |
| B | SER128 | |
| C | ASN55 | |
| C | ASN97 | |
| C | SER123 | |
| C | SER128 | |
| D | ASN55 | |
| D | ASN97 | |
| D | SER123 | |
| D | SER128 | |
| A | ASN55 | |
| A | ASN97 | |
| A | SER123 | |
| A | SER128 | |
| B | ASN55 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20447408 |
| Chain | Residue | Details |
| D | HIS64 | |
| D | GLU68 | |
| D | GLU175 | |
| D | HIS183 | |
| A | HIS183 | |
| B | HIS64 | |
| B | GLU68 | |
| B | GLU175 | |
| B | HIS183 | |
| C | HIS64 | |
| C | GLU68 | |
| C | GLU175 | |
| C | HIS183 | |
| A | HIS64 | |
| A | GLU68 | |
| A | GLU175 |
