5LTZ

GmhA_mutant Q175E

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0008270	molecular_function	zinc ion binding
A	0008968	molecular_function	D-sedoheptulose 7-phosphate isomerase activity
A	0016853	molecular_function	isomerase activity
A	0045227	biological_process	capsule polysaccharide biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0097367	molecular_function	carbohydrate derivative binding
A	1901135	biological_process	carbohydrate derivative metabolic process
A	2001061	biological_process	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0008270	molecular_function	zinc ion binding
B	0008968	molecular_function	D-sedoheptulose 7-phosphate isomerase activity
B	0016853	molecular_function	isomerase activity
B	0045227	biological_process	capsule polysaccharide biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0097367	molecular_function	carbohydrate derivative binding
B	1901135	biological_process	carbohydrate derivative metabolic process
B	2001061	biological_process	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0008270	molecular_function	zinc ion binding
C	0008968	molecular_function	D-sedoheptulose 7-phosphate isomerase activity
C	0016853	molecular_function	isomerase activity
C	0045227	biological_process	capsule polysaccharide biosynthetic process
C	0046872	molecular_function	metal ion binding
C	0097367	molecular_function	carbohydrate derivative binding
C	1901135	biological_process	carbohydrate derivative metabolic process
C	2001061	biological_process	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0008270	molecular_function	zinc ion binding
D	0008968	molecular_function	D-sedoheptulose 7-phosphate isomerase activity
D	0016853	molecular_function	isomerase activity
D	0045227	biological_process	capsule polysaccharide biosynthetic process
D	0046872	molecular_function	metal ion binding
D	0097367	molecular_function	carbohydrate derivative binding
D	1901135	biological_process	carbohydrate derivative metabolic process
D	2001061	biological_process	D-glycero-D-manno-heptose 7-phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue PG4 A 201

Chain	Residue
A	ARG28
A	ALA31
A	THR32
A	LYS35
A	LEU162

---

site_id	AC2
Number of Residues	5
Details	binding site for residue ZN A 202

Chain	Residue
A	I22205
A	HIS64
A	GLU68
A	HIS183
D	GLU175

---

site_id	AC3
Number of Residues	19
Details	binding site for residue I22 A 203

Chain	Residue
A	ASN55
A	GLY56
A	GLY57
A	SER123
A	THR124
A	SER125
A	SER128
A	THR171
A	GLU175
A	HOH319
A	HOH324
A	HOH326
B	ASN97
B	ASP98
D	HIS64
D	GLU68
D	ARG72
D	PHE73
A	ZN204

---

site_id	AC4
Number of Residues	4
Details	binding site for residue PG4 B 201

Chain	Residue
B	GLN110
D	GLU15
D	ASP170
D	NA203

---

site_id	AC5
Number of Residues	3
Details	binding site for residue EDO B 202

Chain	Residue
B	LYS35
B	LEU162
B	HOH310

---

site_id	AC6
Number of Residues	5
Details	binding site for residue ZN B 203

Chain	Residue
B	HIS64
B	GLU68
B	HIS183
C	GLU175
B	I22206

---

site_id	AC7
Number of Residues	18
Details	binding site for residue I22 B 204

Chain	Residue
A	ASN97
A	ASP98
B	ASN55
B	GLY56
B	GLY57
B	SER123
B	THR124
B	SER125
B	SER128
B	GLU175
B	HOH305
B	HOH307
B	HOH325
C	HIS64
C	GLU68
C	PHE73
C	HIS183
B	ZN205

---

site_id	AC8
Number of Residues	4
Details	binding site for residue PGE C 201

Chain	Residue
C	ALA31
C	THR32
C	LYS35
C	LEU162

---

site_id	AC9
Number of Residues	5
Details	binding site for residue ZN B 205

Chain	Residue
B	GLU175
B	I22204
C	HIS64
C	GLU68
C	HIS183

---

site_id	AD1
Number of Residues	19
Details	binding site for residue I22 B 206

Chain	Residue
B	HIS64
B	GLU68
B	PHE73
B	ZN203
B	HOH313
C	ASN55
C	GLY56
C	GLY57
C	SER123
C	THR124
C	SER125
C	SER128
C	THR171
C	GLU175
B	HOH303
C	HOH318
B	HOH333
D	ASN97
D	ASP98

---

site_id	AD2
Number of Residues	4
Details	binding site for residue PEG D 201

Chain	Residue
D	ALA31
D	THR32
D	LYS35
D	LEU162

---

site_id	AD3
Number of Residues	4
Details	binding site for residue GOL D 202

Chain	Residue
C	GLN46
C	HOH306
D	ASP98
D	HOH308

---

site_id	AD4
Number of Residues	1
Details	binding site for residue NA D 203

Chain	Residue
B	PG4201

---

site_id	AD5
Number of Residues	5
Details	binding site for residue ZN A 204

Chain	Residue
D	GLU68
D	HIS183
A	GLU175
A	I22203
D	HIS64

---

site_id	AD6
Number of Residues	18
Details	binding site for residue I22 A 205

Chain	Residue
A	HIS64
A	GLU68
A	ZN202
C	ASN97
C	ASP98
D	ASN55
D	GLY56
D	GLY57
D	SER123
D	THR124
D	SER125
D	SER128
D	THR171
D	GLU175
D	LYS196
D	HOH316
D	HOH326
A	HOH333

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20447408","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	157
Details	Domain: {"description":"SIS"}

Chain

Residue

Details

---