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5LTY

Homeobox transcription factor CDX2 bound to methylated DNA

Functional Information from GO Data
ChainGOidnamespacecontents
K0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
K0003677molecular_functionDNA binding
K0006355biological_processregulation of DNA-templated transcription
M0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
M0003677molecular_functionDNA binding
M0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00027
Number of Residues24
DetailsHOMEOBOX_1 'Homeobox' domain signature. LAatLgLSerQVKIWFqNrrakeR
ChainResidueDetails
KLEU219-ARG242

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues118
DetailsDNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108
ChainResidueDetails
KLYS186-ASN245
MLYS186-ASN245

226707

PDB entries from 2024-10-30

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