Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5LJ3

Structure of the core of the yeast spliceosome immediately after branching

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000350	biological_process	generation of catalytic spliceosome for second transesterification step
A	0000386	molecular_function	second spliceosomal transesterification activity
A	0000387	biological_process	spliceosomal snRNP assembly
A	0000389	biological_process	mRNA 3'-splice site recognition
A	0000395	biological_process	mRNA 5'-splice site recognition
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0005737	cellular_component	cytoplasm
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0017070	molecular_function	U6 snRNA binding
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0097157	molecular_function	pre-mRNA intronic binding
C	0000244	biological_process	spliceosomal tri-snRNP complex assembly
C	0000349	biological_process	generation of catalytic spliceosome for first transesterification step
C	0000387	biological_process	spliceosomal snRNP assembly
C	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005681	cellular_component	spliceosomal complex
C	0005682	cellular_component	U5 snRNP
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0030623	molecular_function	U5 snRNA binding
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
D	0000349	biological_process	generation of catalytic spliceosome for first transesterification step
D	0000350	biological_process	generation of catalytic spliceosome for second transesterification step
D	0000384	molecular_function	first spliceosomal transesterification activity
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005681	cellular_component	spliceosomal complex
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0030620	molecular_function	U2 snRNA binding
D	0046872	molecular_function	metal ion binding
D	0071006	cellular_component	U2-type catalytic step 1 spliceosome
D	0071007	cellular_component	U2-type catalytic step 2 spliceosome
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003674	molecular_function	molecular_function
F	0005634	cellular_component	nucleus
F	0005681	cellular_component	spliceosomal complex
F	0005684	cellular_component	U2-type spliceosomal complex
F	0006397	biological_process	mRNA processing
F	0008380	biological_process	RNA splicing
G	0000350	biological_process	generation of catalytic spliceosome for second transesterification step
G	0000384	molecular_function	first spliceosomal transesterification activity
G	0000389	biological_process	mRNA 3'-splice site recognition
G	0000974	cellular_component	Prp19 complex
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005681	cellular_component	spliceosomal complex
G	0005737	cellular_component	cytoplasm
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
G	0071006	cellular_component	U2-type catalytic step 1 spliceosome
G	0071007	cellular_component	U2-type catalytic step 2 spliceosome
G	0071013	cellular_component	catalytic step 2 spliceosome
G	0071014	cellular_component	post-mRNA release spliceosomal complex
G	0071020	cellular_component	post-spliceosomal complex
H	0003723	molecular_function	RNA binding
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0000974	cellular_component	Prp19 complex
J	0003674	molecular_function	molecular_function
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005681	cellular_component	spliceosomal complex
J	0005737	cellular_component	cytoplasm
J	0006397	biological_process	mRNA processing
J	0008380	biological_process	RNA splicing
J	0071013	cellular_component	catalytic step 2 spliceosome
K	0000350	biological_process	generation of catalytic spliceosome for second transesterification step
K	0000384	molecular_function	first spliceosomal transesterification activity
K	0000386	molecular_function	second spliceosomal transesterification activity
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005681	cellular_component	spliceosomal complex
K	0006397	biological_process	mRNA processing
K	0008380	biological_process	RNA splicing
K	0071006	cellular_component	U2-type catalytic step 1 spliceosome
K	0071007	cellular_component	U2-type catalytic step 2 spliceosome
K	0071014	cellular_component	post-mRNA release spliceosomal complex
L	0000282	biological_process	cellular bud site selection
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0003674	molecular_function	molecular_function
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005681	cellular_component	spliceosomal complex
L	0005686	cellular_component	U2 snRNP
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
M	0000387	biological_process	spliceosomal snRNP assembly
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0000974	cellular_component	Prp19 complex
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005681	cellular_component	spliceosomal complex
M	0006397	biological_process	mRNA processing
M	0008270	molecular_function	zinc ion binding
M	0008380	biological_process	RNA splicing
M	0017070	molecular_function	U6 snRNA binding
M	0033120	biological_process	positive regulation of RNA splicing
M	0036002	molecular_function	pre-mRNA binding
M	0045292	biological_process	mRNA cis splicing, via spliceosome
M	0045787	biological_process	positive regulation of cell cycle
M	0046872	molecular_function	metal ion binding
M	0071006	cellular_component	U2-type catalytic step 1 spliceosome
M	0071007	cellular_component	U2-type catalytic step 2 spliceosome
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0000974	cellular_component	Prp19 complex
N	0003723	molecular_function	RNA binding
N	0005634	cellular_component	nucleus
N	0005681	cellular_component	spliceosomal complex
N	0006397	biological_process	mRNA processing
N	0008380	biological_process	RNA splicing
N	0017070	molecular_function	U6 snRNA binding
N	0036002	molecular_function	pre-mRNA binding
N	0071006	cellular_component	U2-type catalytic step 1 spliceosome
N	0071007	cellular_component	U2-type catalytic step 2 spliceosome
O	0000350	biological_process	generation of catalytic spliceosome for second transesterification step
O	0000386	molecular_function	second spliceosomal transesterification activity
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0000974	cellular_component	Prp19 complex
O	0003677	molecular_function	DNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005681	cellular_component	spliceosomal complex
O	0005737	cellular_component	cytoplasm
O	0006397	biological_process	mRNA processing
O	0008380	biological_process	RNA splicing
O	0071006	cellular_component	U2-type catalytic step 1 spliceosome
P	0000398	biological_process	mRNA splicing, via spliceosome
P	0003674	molecular_function	molecular_function
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005681	cellular_component	spliceosomal complex
P	0005684	cellular_component	U2-type spliceosomal complex
P	0006397	biological_process	mRNA processing
P	0008380	biological_process	RNA splicing
P	0045292	biological_process	mRNA cis splicing, via spliceosome
P	0071013	cellular_component	catalytic step 2 spliceosome
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0003674	molecular_function	molecular_function
R	0005634	cellular_component	nucleus
R	0005681	cellular_component	spliceosomal complex
R	0005684	cellular_component	U2-type spliceosomal complex
R	0005737	cellular_component	cytoplasm
R	0006397	biological_process	mRNA processing
R	0008380	biological_process	RNA splicing
S	0000245	biological_process	spliceosomal complex assembly
S	0000354	biological_process	cis assembly of pre-catalytic spliceosome
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0000785	cellular_component	chromatin
S	0000974	cellular_component	Prp19 complex
S	0003682	molecular_function	chromatin binding
S	0003688	molecular_function	DNA replication origin binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005681	cellular_component	spliceosomal complex
S	0006270	biological_process	DNA replication initiation
S	0006396	biological_process	RNA processing
S	0006397	biological_process	mRNA processing
S	0008380	biological_process	RNA splicing
S	0071004	cellular_component	U2-type prespliceosome
S	0071006	cellular_component	U2-type catalytic step 1 spliceosome
S	0071007	cellular_component	U2-type catalytic step 2 spliceosome
S	0071008	cellular_component	U2-type post-mRNA release spliceosomal complex
S	0071014	cellular_component	post-mRNA release spliceosomal complex
T	0000349	biological_process	generation of catalytic spliceosome for first transesterification step
T	0000384	molecular_function	first spliceosomal transesterification activity
T	0000386	molecular_function	second spliceosomal transesterification activity
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0000974	cellular_component	Prp19 complex
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005681	cellular_component	spliceosomal complex
T	0005829	cellular_component	cytosol
T	0006396	biological_process	RNA processing
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0071004	cellular_component	U2-type prespliceosome
T	0071006	cellular_component	U2-type catalytic step 1 spliceosome
T	0071007	cellular_component	U2-type catalytic step 2 spliceosome
T	0071008	cellular_component	U2-type post-mRNA release spliceosomal complex
T	0071014	cellular_component	post-mRNA release spliceosomal complex
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0003674	molecular_function	molecular_function
W	0005634	cellular_component	nucleus
W	0005681	cellular_component	spliceosomal complex
W	0005686	cellular_component	U2 snRNP
W	0005737	cellular_component	cytoplasm
W	0006397	biological_process	mRNA processing
W	0008380	biological_process	RNA splicing
W	0030620	molecular_function	U2 snRNA binding
W	0071004	cellular_component	U2-type prespliceosome
W	1903241	biological_process	U2-type prespliceosome assembly
Y	0000398	biological_process	mRNA splicing, via spliceosome
Y	0003676	molecular_function	nucleic acid binding
Y	0003723	molecular_function	RNA binding
Y	0005634	cellular_component	nucleus
Y	0005681	cellular_component	spliceosomal complex
Y	0005686	cellular_component	U2 snRNP
Y	0006397	biological_process	mRNA processing
Y	0008380	biological_process	RNA splicing
Y	0030620	molecular_function	U2 snRNA binding
Y	0071004	cellular_component	U2-type prespliceosome
Y	1903241	biological_process	U2-type prespliceosome assembly
Y	1990904	cellular_component	ribonucleoprotein complex
b	0000243	cellular_component	commitment complex
b	0000245	biological_process	spliceosomal complex assembly
b	0000387	biological_process	spliceosomal snRNP assembly
b	0000395	biological_process	mRNA 5'-splice site recognition
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003674	molecular_function	molecular_function
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005681	cellular_component	spliceosomal complex
b	0005682	cellular_component	U5 snRNP
b	0005685	cellular_component	U1 snRNP
b	0005686	cellular_component	U2 snRNP
b	0005687	cellular_component	U4 snRNP
b	0005737	cellular_component	cytoplasm
b	0006397	biological_process	mRNA processing
b	0008380	biological_process	RNA splicing
b	0032991	cellular_component	protein-containing complex
b	0036261	biological_process	7-methylguanosine cap hypermethylation
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0070990	molecular_function	snRNP binding
b	0071001	cellular_component	U4/U6 snRNP
b	0071004	cellular_component	U2-type prespliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	1903241	biological_process	U2-type prespliceosome assembly
b	1990904	cellular_component	ribonucleoprotein complex
d	0000243	cellular_component	commitment complex
d	0000245	biological_process	spliceosomal complex assembly
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000395	biological_process	mRNA 5'-splice site recognition
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0003729	molecular_function	mRNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0006396	biological_process	RNA processing
d	0006397	biological_process	mRNA processing
d	0008380	biological_process	RNA splicing
d	0034715	cellular_component	pICln-Sm protein complex
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0071001	cellular_component	U4/U6 snRNP
d	0071004	cellular_component	U2-type prespliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	0097525	cellular_component	spliceosomal snRNP complex
d	0097526	cellular_component	spliceosomal tri-snRNP complex
d	1903241	biological_process	U2-type prespliceosome assembly
d	1990904	cellular_component	ribonucleoprotein complex
e	0000243	cellular_component	commitment complex
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000395	biological_process	mRNA 5'-splice site recognition
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005737	cellular_component	cytoplasm
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0032991	cellular_component	protein-containing complex
e	0034715	cellular_component	pICln-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0071001	cellular_component	U4/U6 snRNP
e	0071004	cellular_component	U2-type prespliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	1903241	biological_process	U2-type prespliceosome assembly
e	1990935	molecular_function	splicing factor binding
f	0000243	cellular_component	commitment complex
f	0000245	biological_process	spliceosomal complex assembly
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000395	biological_process	mRNA 5'-splice site recognition
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005737	cellular_component	cytoplasm
f	0006397	biological_process	mRNA processing
f	0008266	molecular_function	poly(U) RNA binding
f	0008380	biological_process	RNA splicing
f	0034715	cellular_component	pICln-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0071001	cellular_component	U4/U6 snRNP
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0120114	cellular_component	Sm-like protein family complex
f	1903241	biological_process	U2-type prespliceosome assembly
f	1990935	molecular_function	splicing factor binding
g	0000243	cellular_component	commitment complex
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000395	biological_process	mRNA 5'-splice site recognition
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003674	molecular_function	molecular_function
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005737	cellular_component	cytoplasm
g	0006397	biological_process	mRNA processing
g	0008150	biological_process	biological_process
g	0008380	biological_process	RNA splicing
g	0032991	cellular_component	protein-containing complex
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0071001	cellular_component	U4/U6 snRNP
g	0071004	cellular_component	U2-type prespliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
h	0000243	cellular_component	commitment complex
h	0000245	biological_process	spliceosomal complex assembly
h	0000387	biological_process	spliceosomal snRNP assembly
h	0000395	biological_process	mRNA 5'-splice site recognition
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0003723	molecular_function	RNA binding
h	0003729	molecular_function	mRNA binding
h	0005634	cellular_component	nucleus
h	0005681	cellular_component	spliceosomal complex
h	0005682	cellular_component	U5 snRNP
h	0005685	cellular_component	U1 snRNP
h	0005686	cellular_component	U2 snRNP
h	0005687	cellular_component	U4 snRNP
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0006396	biological_process	RNA processing
h	0006397	biological_process	mRNA processing
h	0008380	biological_process	RNA splicing
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0034715	cellular_component	pICln-Sm protein complex
h	0034719	cellular_component	SMN-Sm protein complex
h	0036261	biological_process	7-methylguanosine cap hypermethylation
h	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
h	0071001	cellular_component	U4/U6 snRNP
h	0071004	cellular_component	U2-type prespliceosome
h	0071011	cellular_component	precatalytic spliceosome
h	0071013	cellular_component	catalytic step 2 spliceosome
h	0097525	cellular_component	spliceosomal snRNP complex
h	0097526	cellular_component	spliceosomal tri-snRNP complex
h	1903241	biological_process	U2-type prespliceosome assembly
h	1990904	cellular_component	ribonucleoprotein complex
j	0000243	cellular_component	commitment complex
j	0000245	biological_process	spliceosomal complex assembly
j	0000387	biological_process	spliceosomal snRNP assembly
j	0000395	biological_process	mRNA 5'-splice site recognition
j	0000398	biological_process	mRNA splicing, via spliceosome
j	0003674	molecular_function	molecular_function
j	0003723	molecular_function	RNA binding
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005681	cellular_component	spliceosomal complex
j	0005682	cellular_component	U5 snRNP
j	0005685	cellular_component	U1 snRNP
j	0005686	cellular_component	U2 snRNP
j	0005687	cellular_component	U4 snRNP
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0006397	biological_process	mRNA processing
j	0008150	biological_process	biological_process
j	0008380	biological_process	RNA splicing
j	0030532	cellular_component	small nuclear ribonucleoprotein complex
j	0032991	cellular_component	protein-containing complex
j	0034715	cellular_component	pICln-Sm protein complex
j	0036261	biological_process	7-methylguanosine cap hypermethylation
j	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
j	0071001	cellular_component	U4/U6 snRNP
j	0071004	cellular_component	U2-type prespliceosome
j	0071011	cellular_component	precatalytic spliceosome
j	0071013	cellular_component	catalytic step 2 spliceosome
j	1903241	biological_process	U2-type prespliceosome assembly
j	1990904	cellular_component	ribonucleoprotein complex
k	0000243	cellular_component	commitment complex
k	0000245	biological_process	spliceosomal complex assembly
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000395	biological_process	mRNA 5'-splice site recognition
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003674	molecular_function	molecular_function
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005737	cellular_component	cytoplasm
k	0006397	biological_process	mRNA processing
k	0008380	biological_process	RNA splicing
k	0032991	cellular_component	protein-containing complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0070990	molecular_function	snRNP binding
k	0071001	cellular_component	U4/U6 snRNP
k	0071004	cellular_component	U2-type prespliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	1903241	biological_process	U2-type prespliceosome assembly
k	1990904	cellular_component	ribonucleoprotein complex
l	0000243	cellular_component	commitment complex
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000395	biological_process	mRNA 5'-splice site recognition
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0003729	molecular_function	mRNA binding
l	0005634	cellular_component	nucleus
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006396	biological_process	RNA processing
l	0006397	biological_process	mRNA processing
l	0008380	biological_process	RNA splicing
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0071001	cellular_component	U4/U6 snRNP
l	0071004	cellular_component	U2-type prespliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	0097525	cellular_component	spliceosomal snRNP complex
l	0097526	cellular_component	spliceosomal tri-snRNP complex
l	1903241	biological_process	U2-type prespliceosome assembly
l	1990904	cellular_component	ribonucleoprotein complex
m	0000243	cellular_component	commitment complex
m	0000245	biological_process	spliceosomal complex assembly
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000395	biological_process	mRNA 5'-splice site recognition
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003674	molecular_function	molecular_function
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0008150	biological_process	biological_process
m	0008380	biological_process	RNA splicing
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0032991	cellular_component	protein-containing complex
m	0034715	cellular_component	pICln-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0071001	cellular_component	U4/U6 snRNP
m	0071004	cellular_component	U2-type prespliceosome
m	0071011	cellular_component	precatalytic spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	1903241	biological_process	U2-type prespliceosome assembly
m	1990904	cellular_component	ribonucleoprotein complex
n	0000243	cellular_component	commitment complex
n	0000245	biological_process	spliceosomal complex assembly
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000395	biological_process	mRNA 5'-splice site recognition
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0003729	molecular_function	mRNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006396	biological_process	RNA processing
n	0006397	biological_process	mRNA processing
n	0008380	biological_process	RNA splicing
n	0034715	cellular_component	pICln-Sm protein complex
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0071001	cellular_component	U4/U6 snRNP
n	0071004	cellular_component	U2-type prespliceosome
n	0071011	cellular_component	precatalytic spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0097525	cellular_component	spliceosomal snRNP complex
n	0097526	cellular_component	spliceosomal tri-snRNP complex
n	1903241	biological_process	U2-type prespliceosome assembly
n	1990904	cellular_component	ribonucleoprotein complex
p	0000243	cellular_component	commitment complex
p	0000245	biological_process	spliceosomal complex assembly
p	0000387	biological_process	spliceosomal snRNP assembly
p	0000395	biological_process	mRNA 5'-splice site recognition
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0003723	molecular_function	RNA binding
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005681	cellular_component	spliceosomal complex
p	0005682	cellular_component	U5 snRNP
p	0005685	cellular_component	U1 snRNP
p	0005686	cellular_component	U2 snRNP
p	0005687	cellular_component	U4 snRNP
p	0005737	cellular_component	cytoplasm
p	0006397	biological_process	mRNA processing
p	0008380	biological_process	RNA splicing
p	0032991	cellular_component	protein-containing complex
p	0034715	cellular_component	pICln-Sm protein complex
p	0036261	biological_process	7-methylguanosine cap hypermethylation
p	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
p	0071001	cellular_component	U4/U6 snRNP
p	0071004	cellular_component	U2-type prespliceosome
p	0071011	cellular_component	precatalytic spliceosome
p	1903241	biological_process	U2-type prespliceosome assembly
p	1990935	molecular_function	splicing factor binding
q	0000243	cellular_component	commitment complex
q	0000245	biological_process	spliceosomal complex assembly
q	0000387	biological_process	spliceosomal snRNP assembly
q	0000395	biological_process	mRNA 5'-splice site recognition
q	0000398	biological_process	mRNA splicing, via spliceosome
q	0003723	molecular_function	RNA binding
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005681	cellular_component	spliceosomal complex
q	0005682	cellular_component	U5 snRNP
q	0005685	cellular_component	U1 snRNP
q	0005686	cellular_component	U2 snRNP
q	0005687	cellular_component	U4 snRNP
q	0005737	cellular_component	cytoplasm
q	0006397	biological_process	mRNA processing
q	0008266	molecular_function	poly(U) RNA binding
q	0008380	biological_process	RNA splicing
q	0034715	cellular_component	pICln-Sm protein complex
q	0036261	biological_process	7-methylguanosine cap hypermethylation
q	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
q	0071001	cellular_component	U4/U6 snRNP
q	0071013	cellular_component	catalytic step 2 spliceosome
q	0120114	cellular_component	Sm-like protein family complex
q	1903241	biological_process	U2-type prespliceosome assembly
q	1990935	molecular_function	splicing factor binding
r	0000243	cellular_component	commitment complex
r	0000245	biological_process	spliceosomal complex assembly
r	0000387	biological_process	spliceosomal snRNP assembly
r	0000395	biological_process	mRNA 5'-splice site recognition
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0003674	molecular_function	molecular_function
r	0003723	molecular_function	RNA binding
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005681	cellular_component	spliceosomal complex
r	0005682	cellular_component	U5 snRNP
r	0005685	cellular_component	U1 snRNP
r	0005686	cellular_component	U2 snRNP
r	0005687	cellular_component	U4 snRNP
r	0005737	cellular_component	cytoplasm
r	0006397	biological_process	mRNA processing
r	0008150	biological_process	biological_process
r	0008380	biological_process	RNA splicing
r	0032991	cellular_component	protein-containing complex
r	0034719	cellular_component	SMN-Sm protein complex
r	0036261	biological_process	7-methylguanosine cap hypermethylation
r	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
r	0071001	cellular_component	U4/U6 snRNP
r	0071004	cellular_component	U2-type prespliceosome
r	0071011	cellular_component	precatalytic spliceosome
r	0071013	cellular_component	catalytic step 2 spliceosome
r	0097526	cellular_component	spliceosomal tri-snRNP complex
r	1903241	biological_process	U2-type prespliceosome assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue MG E 1001

Chain	Residue
E	G-1
V	G60
V	G78

site_id	AC2
Number of Residues	2
Details	binding site for residue MG V 201

Chain	Residue
V	G60
V	U80

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN D 1001

Chain	Residue
D	CYS51
D	CYS54
D	CYS88
D	CYS91

site_id	AC4
Number of Residues	17
Details	binding site for residue GTP C 1101

Chain	Residue
C	LEU142
C	HIS143
C	GLY145
C	LYS146
C	THR147
C	SER148
C	ARG176
C	LEU189
C	SER190
C	ALA215
C	GLY217
C	ASN268
C	LYS269
C	ARG272
C	SER315
C	THR316
C	LYS317

site_id	AC5
Number of Residues	5
Details	binding site for residue ZN L 1000

Chain	Residue
L	CYS104
L	CYS105
L	CYS108
L	CYS148
L	ZN1001

site_id	AC6
Number of Residues	6
Details	binding site for residue ZN L 1001

Chain	Residue
L	CYS104
L	CYS122
L	CYS150
L	CYS153
L	ZN1000
L	ZN1002

site_id	AC7
Number of Residues	6
Details	binding site for residue ZN L 1002

Chain	Residue
L	CYS108
L	CYS120
L	CYS122
L	CYS145
L	CYS150
L	ZN1001

site_id	AC8
Number of Residues	5
Details	binding site for residue ZN M 1000

Chain	Residue
M	CYS73
M	CYS81
M	CYS87
M	HIS91
V	A35

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN N 401

Chain	Residue
N	CYS34
N	CYS37
N	CYS61
N	CYS64

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN N 402

Chain	Residue
N	CYS13
N	CYS16
N	CYS71
N	CYS74

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IATAgrDsVIKLWDM

Chain	Residue	Details
J	ILE239-MET253
J	VAL281-VAL295

site_id	PS00997
Number of Residues	23
Details	G10_1 G10 protein signature 1. LCClRCiqknEtNngstCiCRVP

Chain	Residue	Details
L	LEU103-PRO125

site_id	PS00998
Number of Residues	10
Details	G10_2 G10 protein signature 2. CvHCGCRGCA

Chain	Residue	Details
L	CYS145-ALA154

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	27
Details	ZN_FING: C3H1-type => ECO:0000255\|PROSITE-ProRule:PRU00723

Chain	Residue	Details
M	ASP67-PRO94
O	TRP84-LEU106
C	ASN268
D	CYS91

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19779198

Chain	Residue	Details
M	SER335
M	SER336

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17330950, ECO:0007744\|PubMed:18407956, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
C	THR88

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)