5LG7

Solution NMR structure of Tryptophan to Arginine mutant of Arkadia RING domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0061630	molecular_function	ubiquitin protein ligase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 101

Chain	Residue
A	CYS17
A	CYS20
A	HIS40
A	CYS43

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site_id	AC2
Number of Residues	5
Details	binding site for residue ZN A 102

Chain	Residue
A	CYS35
A	MET36
A	HIS37
A	CYS54
A	CYS57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	41
Details	ZN_FING: RING-type; atypical => ECO:0000255|PROSITE-ProRule:PRU00175

Chain	Residue	Details
A	CYS17-ARG58

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q6ZSG1

Chain	Residue	Details
A	CYS17
A	CYS20
A	HIS40
A	CYS43

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS2

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