5L9W
Crystal structure of the Apc core complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0017168 | molecular_function | 5-oxoprolinase (ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016874 | molecular_function | ligase activity |
| B | 0017168 | molecular_function | 5-oxoprolinase (ATP-hydrolyzing) activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016874 | molecular_function | ligase activity |
| b | 0005524 | molecular_function | ATP binding |
| b | 0005737 | cellular_component | cytoplasm |
| b | 0005829 | cellular_component | cytosol |
| b | 0006749 | biological_process | glutathione metabolic process |
| b | 0016787 | molecular_function | hydrolase activity |
| b | 0016874 | molecular_function | ligase activity |
| b | 0017168 | molecular_function | 5-oxoprolinase (ATP-hydrolyzing) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue HG A 701 |
| Chain | Residue |
| A | ASP65 |
| A | HIS123 |
| A | ASP126 |
| A | HIS148 |
| A | HOH803 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue HG A 702 |
| Chain | Residue |
| A | CYS82 |
| A | HOH805 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue K A 703 |
| Chain | Residue |
| A | ASN501 |
| A | THR365 |
| A | ASP500 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EPE A 704 |
| Chain | Residue |
| A | PRO201 |
| A | SER202 |
| A | GLN404 |
| A | GLY408 |
| A | SER409 |
| A | SER410 |
| B | GLY616 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue HG B 801 |
| Chain | Residue |
| B | LYS36 |
| B | CYS37 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue EPE B 802 |
| Chain | Residue |
| B | VAL217 |
| B | VAL218 |
| B | SER219 |
| B | LYS274 |
| B | TYR512 |
| B | GLU513 |
| B | ARG545 |
| B | GLU549 |
| b | GLN165 |
| b | ILE170 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | binding site for residue ADP b 801 |
| Chain | Residue |
| b | THR11 |
| b | MET12 |
| b | ASP14 |
| b | ASP274 |
| b | VAL275 |
| b | GLY276 |
| b | GLY277 |
| b | THR354 |
| b | PHE368 |
| b | LEU369 |
| b | GLY436 |
| b | ASN437 |
| b | GLY631 |
| b | SER632 |
| b | THR635 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EPE b 802 |
| Chain | Residue |
| b | HIS33 |
| b | ASP34 |
| b | TYR35 |
| b | THR36 |
| b | SER208 |
| b | LYS211 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue HG C 201 |
| Chain | Residue |
| C | CYS22 |
| C | CYS25 |
| C | CYS75 |
| C | CYS78 |
| C | ARG80 |
