Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 601 |
| Chain | Residue |
| A | ARG50 |
| A | ARG272 |
| A | GOL602 |
| A | HOH805 |
| B | LYS378 |
| B | ASN382 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 602 |
| Chain | Residue |
| A | GOL601 |
| A | HOH719 |
| B | GLN365 |
| A | ASN31 |
| A | ARG50 |
| A | LYS425 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 603 |
| Chain | Residue |
| A | HIS73 |
| A | CYS109 |
| A | MET110 |
| A | SER111 |
| A | THR112 |
| A | GOL605 |
| B | GLU536 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 604 |
| Chain | Residue |
| A | LYS318 |
| A | SER319 |
| A | GLY359 |
| A | HOH715 |
| A | HOH718 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | SER111 |
| A | THR112 |
| A | GOL603 |
| A | HOH709 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 606 |
| Chain | Residue |
| A | HIS73 |
| A | LYS100 |
| A | ARG114 |
| A | ARG527 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 607 |
| Chain | Residue |
| A | LYS168 |
| A | ARG193 |
| A | LYS202 |
| A | LYS205 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 601 |
| Chain | Residue |
| A | LYS378 |
| A | ASN382 |
| B | ARG50 |
| B | ARG272 |
| B | THR317 |
| B | GOL602 |
| B | HOH821 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 602 |
| Chain | Residue |
| A | GLU404 |
| B | ASN31 |
| B | GOL601 |
| B | HOH745 |
| B | HOH752 |
| B | HOH798 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 603 |
| Chain | Residue |
| B | LYS168 |
| B | ARG193 |
| B | LYS205 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 604 |
| Chain | Residue |
| B | HIS73 |
| B | LYS100 |
| B | ARG527 |
| B | GOL607 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 605 |
| Chain | Residue |
| B | THR112 |
| B | ASN157 |
| B | GOL607 |
| B | HOH710 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 606 |
| Chain | Residue |
| B | SER319 |
| B | GLY360 |
| B | SER362 |
| B | THR380 |
| B | HOH825 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 607 |
| Chain | Residue |
| A | GLU536 |
| B | HIS73 |
| B | CYS109 |
| B | MET110 |
| B | THR112 |
| B | GOL604 |
| B | GOL605 |
| B | HOH703 |
| B | HOH710 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LISAssDtTVKVWNA |
| Chain | Residue | Details |
| A | LEU90-ALA104 | |
| A | VAL132-VAL146 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 8","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q8BH57","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
5L8E
