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5L87

Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.

Functional Information from GO Data
ChainGOidnamespacecontents
A0005778cellular_componentperoxisomal membrane
A0016560biological_processprotein import into peroxisome matrix, docking
Functional Information from PDB Data
site_idAC1
Number of Residues19
Detailsbinding site for residue 6RD A 101
ChainResidue
AASN13
ALYS38
AARG63
AHOH235
AHOH257
AHOH257
AHOH266
AHOH325
AHOH328
AHOH329
AHOH331
AGLU16
AASP20
AARG22
AVAL23
AHIS33
APHE34
ALEU35
ASER37

site_idAC2
Number of Residues8
Detailsbinding site for residue EDO A 102
ChainResidue
ALYS56
ALYS56
ATHR57
ATHR57
AHOH214
AHOH214
AHOH255
AHOH255

217705

PDB entries from 2024-03-27

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