Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS218 |
| A | HIS222 |
| A | HIS228 |
| A | R47309 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 302 |
| Chain | Residue |
| A | HIS168 |
| A | ASP170 |
| A | HIS183 |
| A | HIS196 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 303 |
| Chain | Residue |
| A | GLY176 |
| A | GLY178 |
| A | ILE180 |
| A | ASP198 |
| A | GLU201 |
| A | ASP175 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 304 |
| Chain | Residue |
| A | ASP158 |
| A | GLY190 |
| A | GLY192 |
| A | ASP194 |
| A | HOH436 |
| A | HOH446 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 305 |
| Chain | Residue |
| A | ASP124 |
| A | GLU199 |
| A | GLU201 |
| A | HOH532 |
| A | HOH533 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | GLY209 |
| A | THR210 |
| A | R47309 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | PRO123 |
| A | MET125 |
| A | ASN126 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 302 |
| Chain | Residue |
| B | HIS218 |
| B | HIS222 |
| B | HIS228 |
| B | R47307 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 303 |
| Chain | Residue |
| B | HIS168 |
| B | ASP170 |
| B | HIS183 |
| B | HIS196 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 304 |
| Chain | Residue |
| B | ASP175 |
| B | GLY176 |
| B | GLY178 |
| B | ILE180 |
| B | ASP198 |
| B | GLU201 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 305 |
| Chain | Residue |
| B | ASP158 |
| B | GLY190 |
| B | GLY192 |
| B | ASP194 |
| B | HOH430 |
| B | HOH449 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 306 |
| Chain | Residue |
| B | ASP124 |
| B | GLU199 |
| B | GLU201 |
| B | HOH531 |
| B | HOH540 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| A | SER229 |
| B | SER229 |
| B | SER230 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 309 |
| Chain | Residue |
| B | LEU181 |
| B | GLY209 |
| B | THR210 |
| B | TYR240 |
| B | R47307 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 310 |
| Chain | Residue |
| B | HIS183 |
| B | ALA184 |
| B | PHE185 |
| B | R47307 |
| site_id | AD7 |
| Number of Residues | 44 |
| Details | binding site for residues 6PJ A 306 and R47 B 306 |
| Chain | Residue |
| B | PHE237 |
| B | PRO238 |
| B | THR239 |
| B | TYR240 |
| B | ALA241 |
| B | VAL243 |
| B | ZN302 |
| B | GOL309 |
| B | DMS310 |
| B | HOH443 |
| B | HOH464 |
| B | HOH472 |
| B | HOH507 |
| A | SER230 |
| A | PRO232 |
| A | LYS233 |
| A | TYR242 |
| A | VAL243 |
| A | ARG249 |
| A | SER251 |
| A | ALA252 |
| B | HOH401 |
| B | HOH407 |
| B | HOH414 |
| B | HOH422 |
| B | HOH459 |
| B | HOH463 |
| A | HOH475 |
| B | ARG110 |
| B | LYS111 |
| B | GLY178 |
| B | GLY179 |
| B | ILE180 |
| B | LEU181 |
| B | ALA182 |
| B | THR215 |
| B | HIS218 |
| B | GLU219 |
| B | HIS222 |
| B | HIS228 |
| B | PRO232 |
| B | LYS233 |
| B | ALA234 |
| B | VAL235 |
| site_id | AD8 |
| Number of Residues | 55 |
| Details | binding site for residues R47 A 310 and 6PJ B 309 |
| Chain | Residue |
| A | VAL108 |
| A | TRP109 |
| A | ARG110 |
| A | PRO123 |
| A | MET125 |
| A | ASN126 |
| A | GLY179 |
| A | ILE180 |
| A | LEU181 |
| A | ALA182 |
| A | PRO187 |
| A | GLY188 |
| A | SER189 |
| A | THR215 |
| A | HIS218 |
| A | GLU219 |
| A | HIS222 |
| A | HIS228 |
| A | PRO232 |
| A | LYS233 |
| A | ALA234 |
| A | VAL235 |
| A | PHE237 |
| A | PRO238 |
| A | THR239 |
| A | TYR240 |
| A | ALA241 |
| A | VAL243 |
| A | ZN301 |
| A | EDO307 |
| A | HOH412 |
| A | HOH414 |
| A | HOH455 |
| A | HOH458 |
| A | HOH498 |
| A | HOH518 |
| A | HOH523 |
| B | HIS183 |
| B | ALA184 |
| B | PHE185 |
| B | SER230 |
| B | PRO232 |
| B | LYS233 |
| B | THR247 |
| B | PHE248 |
| B | ARG249 |
| B | SER251 |
| B | ALA252 |
| B | R47307 |
| B | HOH404 |
| A | HOH402 |
| A | HOH421 |
| A | HOH438 |
| A | HOH468 |
| A | HOH486 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TAVHEIGHSL |
| Chain | Residue | Details |
| A | THR215-LEU224 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | Binding site: {} |
