5L0P

Symmetry-based assembly of a two-dimensional protein lattice

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Breakpoint for translocation to form CHIC2-ETV6 in AML

Chain	Residue	Details
A	THR148

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Breakpoint for translocation to form ETV6-MDS2 in MDS

Chain	Residue	Details
A	LEU189

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Breakpoint for translocation to form PAX5-ETV6

Chain	Residue	Details
A	ARG190

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	THR148

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	ARG155

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:12435397, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
A	SER159

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site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	THR148

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site_id	SWS_FT_FI8
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	HIS301
A	GLU349

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