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5L08

Cryo-EM structure of Casp-8 tDED filament

Functional Information from GO Data
ChainGOidnamespacecontents
A0004197molecular_functioncysteine-type endopeptidase activity
A0006508biological_processproteolysis
A0006915biological_processapoptotic process
A0042981biological_processregulation of apoptotic process
B0004197molecular_functioncysteine-type endopeptidase activity
B0006508biological_processproteolysis
B0006915biological_processapoptotic process
B0042981biological_processregulation of apoptotic process
C0004197molecular_functioncysteine-type endopeptidase activity
C0006508biological_processproteolysis
C0006915biological_processapoptotic process
C0042981biological_processregulation of apoptotic process
D0004197molecular_functioncysteine-type endopeptidase activity
D0006508biological_processproteolysis
D0006915biological_processapoptotic process
D0042981biological_processregulation of apoptotic process
E0004197molecular_functioncysteine-type endopeptidase activity
E0006508biological_processproteolysis
E0006915biological_processapoptotic process
E0042981biological_processregulation of apoptotic process
F0004197molecular_functioncysteine-type endopeptidase activity
F0006508biological_processproteolysis
F0006915biological_processapoptotic process
F0042981biological_processregulation of apoptotic process
G0004197molecular_functioncysteine-type endopeptidase activity
G0006508biological_processproteolysis
G0006915biological_processapoptotic process
G0042981biological_processregulation of apoptotic process
H0004197molecular_functioncysteine-type endopeptidase activity
H0006508biological_processproteolysis
H0006915biological_processapoptotic process
H0042981biological_processregulation of apoptotic process
I0004197molecular_functioncysteine-type endopeptidase activity
I0006508biological_processproteolysis
I0006915biological_processapoptotic process
I0042981biological_processregulation of apoptotic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9
DetailsSITE: Cleavage; by autocatalytic cleavage => ECO:0000269|PubMed:8962078, ECO:0000269|PubMed:9184224
ChainResidueDetails
ALEU157
BLEU157
CLEU157
DLEU157
ELEU157
FLEU157
GLEU157
HLEU157
ILEU157

site_idSWS_FT_FI2
Number of Residues18
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O89110
ChainResidueDetails
ASER129
ELEU152
FSER129
FLEU152
GSER129
GLEU152
HSER129
HLEU152
ISER129
ILEU152
ALEU152
BSER129
BLEU152
CSER129
CLEU152
DSER129
DLEU152
ESER129

site_idSWS_FT_FI3
Number of Residues9
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O89110
ChainResidueDetails
AALA165
BALA165
CALA165
DALA165
EALA165
FALA165
GALA165
HALA165
IALA165

Catalytic Information from CSA
site_idMCSA1
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

site_idMCSA2
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

site_idMCSA3
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

site_idMCSA4
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

site_idMCSA5
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

site_idMCSA6
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

site_idMCSA7
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

site_idMCSA8
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

site_idMCSA9
Number of Residues
DetailsM-CSA 818
ChainResidueDetails

227111

PDB entries from 2024-11-06

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