5KY4

mouse POFUT1 in complex with mouse Notch1 EGF26 and GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001525	biological_process	angiogenesis
A	0001756	biological_process	somitogenesis
A	0005783	cellular_component	endoplasmic reticulum
A	0006004	biological_process	fucose metabolic process
A	0006486	biological_process	protein glycosylation
A	0006493	biological_process	protein O-linked glycosylation
A	0007219	biological_process	Notch signaling pathway
A	0007399	biological_process	nervous system development
A	0007507	biological_process	heart development
A	0008417	molecular_function	fucosyltransferase activity
A	0008593	biological_process	regulation of Notch signaling pathway
A	0016020	cellular_component	membrane
A	0016757	molecular_function	glycosyltransferase activity
A	0036066	biological_process	protein O-linked fucosylation
A	0046922	molecular_function	peptide-O-fucosyltransferase activity
B	0005509	molecular_function	calcium ion binding

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CvDginsFtClC

Chain	Residue	Details
B	CYS980-CYS991

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site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. ClCppGftGSyC

Chain	Residue	Details
B	CYS989-CYS1000

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site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. ClCppGFtgsy....C

Chain	Residue	Details
B	CYS989-CYS1000

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: O-linked (Glc...) serine => ECO:0000269|PubMed:21757702

Chain	Residue	Details
B	CYS991
A	HIS243
A	ASP345
A	SER362

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
B	TYR999
A	ASN165

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