5KTY
hMiro EF hand and cGTPase domains, GDP and Ca2+ bound state
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue GDP A 701 |
| Chain | Residue |
| A | ASN428 |
| A | ASP530 |
| A | LEU531 |
| A | THR558 |
| A | CYS559 |
| A | ASN560 |
| A | MG702 |
| A | GDP703 |
| A | HOH802 |
| A | HOH818 |
| A | HOH855 |
| A | CYS429 |
| A | GLY430 |
| A | LYS431 |
| A | SER432 |
| A | GLY433 |
| A | LEU443 |
| A | LYS447 |
| A | LYS528 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 702 |
| Chain | Residue |
| A | ASN428 |
| A | GDP701 |
| A | GDP703 |
| A | HOH802 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue GDP A 703 |
| Chain | Residue |
| A | LYS427 |
| A | ASN428 |
| A | LYS431 |
| A | LYS454 |
| A | TYR456 |
| A | TYR456 |
| A | ASP475 |
| A | SER477 |
| A | SER477 |
| A | GLU478 |
| A | GDP701 |
| A | MG702 |
| A | HOH802 |
| A | HOH816 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 704 |
| Chain | Residue |
| A | ASP197 |
| A | ASP199 |
| A | ASP201 |
| A | THR203 |
| A | GLU208 |
| A | HOH829 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 705 |
| Chain | Residue |
| A | ASP317 |
| A | ASP319 |
| A | ASP321 |
| A | ALA323 |
| A | GLU328 |
| A | HOH819 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DQDNDGTLNdaEL |
| Chain | Residue | Details |
| A | ASP197-LEU209 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 163 |
| Details | Domain: {"description":"Miro 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00757","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KTY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5KSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KSP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KU1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5KSP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5KSO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"27605430","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
