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5KT6

Teranry complex of human DNA polymerase iota(1-445) inserting dCMPNPP opposite template G in the presence of Mg2+

Functional Information from GO Data
ChainGOidnamespacecontents
A0003684molecular_functiondamaged DNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues18
Detailsbinding site for residue 0KX A 501
ChainResidue
AASP59
AARG96
ALYS102
AASP151
ALYS239
AMG502
AMG503
PDC873
TDG840
TDG841
ALEU60
AASP61
ACYS62
APHE63
ATYR64
AVAL89
ATHR90
ATYR93

site_idAC2
Number of Residues5
Detailsbinding site for residue MG A 502
ChainResidue
AASP59
ALEU60
AASP151
A0KX501
AMG503

site_idAC3
Number of Residues6
Detailsbinding site for residue MG A 503
ChainResidue
AASP59
AASP151
AGLU152
A0KX501
AMG502
PDC873

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00216
ChainResidueDetails
AGLU152

site_idSWS_FT_FI2
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:27555320, ECO:0007744|PDB:5KT5
ChainResidueDetails
AASP59
ALEU60
AASP151

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:15254543, ECO:0007744|PDB:1T3N
ChainResidueDetails
ATYR64
AARG96

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PDB entries from 2024-11-06

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