5KSZ

hMiro EF hand and cGTPase domains in the GMPPCP-bound state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005509	molecular_function	calcium ion binding
A	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 701

Chain	Residue
A	ASP197
A	ASP199
A	ASP201
A	THR203
A	GLU208
A	HOH804

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 702

Chain	Residue
A	ALA323
A	GLU328
A	HOH801
A	ASP317
A	ASP319
A	ASP321

---

site_id	AC3
Number of Residues	17
Details	binding site for residue GCP A 703

Chain	Residue
A	LYS427
A	ASN428
A	CYS429
A	GLY430
A	LYS431
A	SER432
A	GLY433
A	LEU443
A	LYS447
A	ASP475
A	LYS528
A	ASP530
A	LEU531
A	THR558
A	CYS559
A	ASN560
A	HOH812

---

site_id	AC4
Number of Residues	3
Details	binding site for residue CL A 704

Chain	Residue
A	ARG191
A	PHE274
A	TYR286

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DQDNDGTLNdaEL

Chain	Residue	Details
A	ASP197-LEU209

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448

Chain	Residue	Details
A	ASP197
A	ASP199
A	ASP201
A	THR203
A	GLU208

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	ASP317
A	ASP319
A	ASP321
A	GLU328

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING:

Chain	Residue	Details
A	GLY425

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	TYR463
A	ALA527

---