5KRS

HIV-1 Integrase Catalytic Core Domain in Complex with an Allosteric Inhibitor, 3-(1H-pyrrol-1-yl)-2-thiophenecarboxylic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue DMS A 301

Chain	Residue
A	TRP131

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site_id	AC2
Number of Residues	12
Details	binding site for residue 6XI A 302

Chain	Residue
A	HOH419
A	HOH448
A	HOH467
A	HOH485
A	CAF65
A	GLU92
A	THR93
A	GLY94
A	SER119
A	ASN120
A	THR122
A	SER123

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site_id	AC3
Number of Residues	3
Details	binding site for residue 6XI A 303

Chain	Residue
A	GLU170
A	HOH401
A	HOH438

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
A	ASP64
A	ASP116

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P04585

Chain	Residue	Details
A	GLU152

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