5KO8
Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN and mono-iodotyrosine (I-Tyr)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0140616 | molecular_function | iodotyrosine deiodinase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0140616 | molecular_function | iodotyrosine deiodinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue FMN A 301 |
| Chain | Residue |
| A | ARG34 |
| A | SER150 |
| A | LEU170 |
| A | THR171 |
| A | HIS172 |
| A | THR173 |
| A | ARG212 |
| A | IYR302 |
| A | HOH418 |
| A | HOH424 |
| A | HOH427 |
| A | ARG35 |
| A | HOH434 |
| A | HOH440 |
| A | THR36 |
| A | ARG38 |
| A | PRO61 |
| A | SER62 |
| A | HIS65 |
| A | PHE110 |
| A | THR112 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue IYR A 302 |
| Chain | Residue |
| A | ARG38 |
| A | GLY63 |
| A | ALA64 |
| A | GLU91 |
| A | TYR95 |
| A | LEU107 |
| A | PHE110 |
| A | THR112 |
| A | ASP113 |
| A | LYS116 |
| A | HIS172 |
| A | FMN301 |
| A | HOH401 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue FMN B 301 |
| Chain | Residue |
| B | ARG34 |
| B | ARG35 |
| B | THR36 |
| B | ARG38 |
| B | PRO61 |
| B | SER62 |
| B | HIS65 |
| B | PHE110 |
| B | GLU149 |
| B | LEU170 |
| B | THR171 |
| B | THR173 |
| B | ARG212 |
| B | IYR302 |
| B | HOH416 |
| B | HOH417 |
| B | HOH422 |
| B | HOH425 |
| B | HOH437 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue IYR B 302 |
| Chain | Residue |
| B | ARG38 |
| B | GLY63 |
| B | ALA64 |
| B | GLU91 |
| B | TYR95 |
| B | LEU107 |
| B | PHE110 |
| B | THR112 |
| B | LYS116 |
| B | FMN301 |
| B | HOH436 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28157283","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KO7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KO8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KRD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28157283","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KO8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KRD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28157283","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KO8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
