Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5KNC

Crystal structure of the 3 ADP-bound V1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0006814	biological_process	sodium ion transport
A	0035725	biological_process	sodium ion transmembrane transport
A	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0046034	biological_process	ATP metabolic process
A	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0006814	biological_process	sodium ion transport
B	0035725	biological_process	sodium ion transmembrane transport
B	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0046034	biological_process	ATP metabolic process
B	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0006814	biological_process	sodium ion transport
C	0035725	biological_process	sodium ion transmembrane transport
C	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0046034	biological_process	ATP metabolic process
C	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0006814	biological_process	sodium ion transport
D	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
D	0046034	biological_process	ATP metabolic process
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0006814	biological_process	sodium ion transport
E	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
E	0046034	biological_process	ATP metabolic process
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0006814	biological_process	sodium ion transport
F	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
F	0046034	biological_process	ATP metabolic process
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005524	molecular_function	ATP binding
G	0006814	biological_process	sodium ion transport
G	0033176	cellular_component	proton-transporting V-type ATPase complex
G	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005524	molecular_function	ATP binding
H	0006814	biological_process	sodium ion transport
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 701

Chain	Residue
A	THR239
A	SO4702
A	ADP703
A	HOH801
A	HOH804
D	ARG350

site_id	AC2
Number of Residues	12
Details	binding site for residue SO4 A 702

Chain	Residue
A	ARG262
A	ARG333
A	SER391
A	MG701
A	ADP703
A	HOH801
A	HOH802
A	HOH804
D	ARG350
A	PRO233
A	PHE234
A	LYS238

site_id	AC3
Number of Residues	16
Details	binding site for residue ADP A 703

Chain	Residue
A	PRO233
A	GLY235
A	ALA236
A	GLY237
A	LYS238
A	THR239
A	VAL240
A	PHE425
A	GLN503
A	ASN504
A	ALA505
A	PHE506
A	MG701
A	SO4702
A	HOH801
D	ARG350

site_id	AC4
Number of Residues	5
Details	binding site for residue GOL A 704

Chain	Residue
A	SER360
A	ARG361
A	GLU364
A	GOL705
E	GLU259

site_id	AC5
Number of Residues	3
Details	binding site for residue GOL A 705

Chain	Residue
A	GLU364
A	GOL704
E	ASN215

site_id	AC6
Number of Residues	1
Details	binding site for residue GOL A 706

Chain	Residue
A	ASN101

site_id	AC7
Number of Residues	3
Details	binding site for residue GOL A 707

Chain	Residue
A	GLN25
A	GLU38
A	ARG361

site_id	AC8
Number of Residues	8
Details	binding site for residue GOL A 708

Chain	Residue
A	THR239
A	HIS243
A	TYR256
A	GLU261
A	GLU265
A	VAL269
A	ASP329
A	HOH804

site_id	AC9
Number of Residues	4
Details	binding site for residue GOL A 709

Chain	Residue
A	ASP416
A	ASN429
A	TRP430
A	ILE431

site_id	AD1
Number of Residues	8
Details	binding site for residue MG B 601

Chain	Residue
B	THR239
B	GLU261
B	ARG262
B	ADP602
B	HOH702
B	HOH703
B	HOH707
B	HOH708

site_id	AD2
Number of Residues	16
Details	binding site for residue ADP B 602

Chain	Residue
B	PRO233
B	GLY235
B	ALA236
B	GLY237
B	LYS238
B	THR239
B	VAL240
B	PHE425
B	GLN503
B	ASN504
B	ALA505
B	PHE506
B	MG601
B	HOH703
B	HOH708
E	ARG350

site_id	AD3
Number of Residues	4
Details	binding site for residue GOL B 603

Chain	Residue
B	LYS224
B	ASP250
B	ASN280
B	ASP323

site_id	AD4
Number of Residues	4
Details	binding site for residue GOL B 604

Chain	Residue
B	GLY395
B	ILE397
B	LEU415
B	ASN429

site_id	AD5
Number of Residues	3
Details	binding site for residue GOL B 605

Chain	Residue
B	ASP416
B	TRP430
B	GLU468

site_id	AD6
Number of Residues	3
Details	binding site for residue GOL B 606

Chain	Residue
B	GLN403
F	ASP309
F	ARG331

site_id	AD7
Number of Residues	3
Details	binding site for residue GOL B 607

Chain	Residue
B	GLY0
B	ASP507
B	TYR561

site_id	AD8
Number of Residues	6
Details	binding site for residue MG C 601

Chain	Residue
C	THR239
C	GLU261
C	ADP602
C	HOH701
C	HOH703
C	HOH709

site_id	AD9
Number of Residues	15
Details	binding site for residue ADP C 602

Chain	Residue
C	GLY235
C	ALA236
C	GLY237
C	LYS238
C	THR239
C	VAL240
C	PHE425
C	ALA505
C	PHE506
C	MG601
C	HOH701
C	HOH710
F	SER349
F	ARG350
F	ASP353

site_id	AE1
Number of Residues	6
Details	binding site for residue GOL D 501

Chain	Residue
C	GLN403
C	GLN432
D	SER153
D	GLU308
D	ASP309
D	ARG331

site_id	AE2
Number of Residues	4
Details	binding site for residue GOL D 502

Chain	Residue
A	PHE102
D	GLU114
D	GLU233
D	GLU238

site_id	AE3
Number of Residues	5
Details	binding site for residue GOL F 501

Chain	Residue
C	GLU352
C	SER393
C	GLY394
F	ARG270
G	THR8

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PPIDVLPSLS

Chain	Residue	Details
D	PRO340-SER349
A	PRO426-SER435

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY232
B	GLY232
C	GLY232

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)