5KKP

Crystal Structure of Human Pseudouridylate Synthase 7

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001522	biological_process	pseudouridine synthesis
A	0003723	molecular_function	RNA binding
A	0009451	biological_process	RNA modification
A	0009982	molecular_function	pseudouridine synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue EDO A 701

Chain	Residue
A	TYR375
A	ARG379
A	SER632
A	TYR634

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Functional Information from PROSITE/UniProt

site_id	PS01268
Number of Residues	14
Details	UPF0024 Uncharacterized protein family UPF0024 signature. GtKDKrAITvQeIA

Chain	Residue	Details
A	GLY291-ALA304

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000305|PubMed:29628141, ECO:0000305|PubMed:34718722

Chain	Residue	Details
A	ASP294

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER127

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	THR610

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