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5KHO

Rasip1 RA domain in complex with Rap1B

Functional Information from GO Data
ChainGOidnamespacecontents
A0007165biological_processsignal transduction
B0007165biological_processsignal transduction
C0003924molecular_functionGTPase activity
C0003925molecular_functionG protein activity
C0005515molecular_functionprotein binding
C0005525molecular_functionGTP binding
C0005737cellular_componentcytoplasm
C0005811cellular_componentlipid droplet
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0005911cellular_componentcell-cell junction
C0007165biological_processsignal transduction
C0007264biological_processsmall GTPase-mediated signal transduction
C0008283biological_processcell population proliferation
C0016020cellular_componentmembrane
C0016787molecular_functionhydrolase activity
C0017156biological_processcalcium-ion regulated exocytosis
C0019003molecular_functionGDP binding
C0030033biological_processmicrovillus assembly
C0032486biological_processRap protein signal transduction
C0033625biological_processpositive regulation of integrin activation
C0035577cellular_componentazurophil granule membrane
C0044877molecular_functionprotein-containing complex binding
C0045121cellular_componentmembrane raft
C0045955biological_processnegative regulation of calcium ion-dependent exocytosis
C0051649biological_processestablishment of localization in cell
C0061028biological_processestablishment of endothelial barrier
C0070062cellular_componentextracellular exosome
C0070161cellular_componentanchoring junction
C0070374biological_processpositive regulation of ERK1 and ERK2 cascade
C0071320biological_processcellular response to cAMP
C0098978cellular_componentglutamatergic synapse
C0099010biological_processmodification of postsynaptic structure
C1901888biological_processregulation of cell junction assembly
C2000114biological_processregulation of establishment of cell polarity
C2000301biological_processnegative regulation of synaptic vesicle exocytosis
D0003924molecular_functionGTPase activity
D0003925molecular_functionG protein activity
D0005515molecular_functionprotein binding
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005811cellular_componentlipid droplet
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0005911cellular_componentcell-cell junction
D0007165biological_processsignal transduction
D0007264biological_processsmall GTPase-mediated signal transduction
D0008283biological_processcell population proliferation
D0016020cellular_componentmembrane
D0016787molecular_functionhydrolase activity
D0017156biological_processcalcium-ion regulated exocytosis
D0019003molecular_functionGDP binding
D0030033biological_processmicrovillus assembly
D0032486biological_processRap protein signal transduction
D0033625biological_processpositive regulation of integrin activation
D0035577cellular_componentazurophil granule membrane
D0044877molecular_functionprotein-containing complex binding
D0045121cellular_componentmembrane raft
D0045955biological_processnegative regulation of calcium ion-dependent exocytosis
D0051649biological_processestablishment of localization in cell
D0061028biological_processestablishment of endothelial barrier
D0070062cellular_componentextracellular exosome
D0070161cellular_componentanchoring junction
D0070374biological_processpositive regulation of ERK1 and ERK2 cascade
D0071320biological_processcellular response to cAMP
D0098978cellular_componentglutamatergic synapse
D0099010biological_processmodification of postsynaptic structure
D1901888biological_processregulation of cell junction assembly
D2000114biological_processregulation of establishment of cell polarity
D2000301biological_processnegative regulation of synaptic vesicle exocytosis
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue GOL A 301
ChainResidue
AASP206
AARG227
AVAL238
ATRP242
AARG250
BASP206
BARG227
BTRP242

site_idAC2
Number of Residues5
Detailsbinding site for residue MG C 200
ChainResidue
CTHR35
CGNP201
CHOH302
CHOH303
CSER17

site_idAC3
Number of Residues24
Detailsbinding site for residue GNP C 201
ChainResidue
BGLU258
CGLY13
CVAL14
CGLY15
CLYS16
CSER17
CALA18
CPHE28
CVAL29
CGLU30
CTYR32
CPRO34
CTHR35
CGLY60
CASN116
CLYS117
CASP119
CLEU120
CSER147
CALA148
CLYS149
CMG200
CHOH302
CHOH303

site_idAC4
Number of Residues5
Detailsbinding site for residue MG D 200
ChainResidue
DSER17
DTHR35
DGNP201
DHOH301
DHOH302

site_idAC5
Number of Residues21
Detailsbinding site for residue GNP D 201
ChainResidue
DGLY13
DVAL14
DGLY15
DLYS16
DSER17
DALA18
DPHE28
DVAL29
DGLU30
DTYR32
DTHR35
DGLY60
DASN116
DLYS117
DASP119
DLEU120
DSER147
DALA148
DMG200
DHOH301
DHOH302

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:18309292, ECO:0000269|PubMed:22577140
ChainResidueDetails
CGLY10
CASP57
CASN116
CSER147
DGLY10
DASP57
DASN116
DSER147

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: ADP-ribosylserine; by botulinum toxin => ECO:0000305|PubMed:3141412
ChainResidueDetails
CSER39
DSER39

223790

PDB entries from 2024-08-14

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