5KHJ
HCN2 CNBD in complex with uridine-3', 5'-cyclic monophosphate (cUMP)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 6SY A 701 |
| Chain | Residue |
| A | MET572 |
| A | ARG632 |
| A | ARG635 |
| A | ILE636 |
| A | PHE580 |
| A | GLY581 |
| A | GLU582 |
| A | ILE583 |
| A | CYS584 |
| A | ARG591 |
| A | THR592 |
| A | ALA593 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue 6SY B 701 |
| Chain | Residue |
| B | MET572 |
| B | PHE580 |
| B | GLY581 |
| B | GLU582 |
| B | ILE583 |
| B | CYS584 |
| B | ARG591 |
| B | THR592 |
| B | ALA593 |
| B | ARG632 |
| B | ARG635 |
Functional Information from PROSITE/UniProt
| site_id | PS00888 |
| Number of Residues | 17 |
| Details | CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrEGTiGKkMYFIqhG |
| Chain | Residue | Details |
| A | ILE544-GLY560 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18367452","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19525958","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BPZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by PKG/PRKG2","evidences":[{"source":"PubMed","id":"21347269","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
