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5KH2

Crystal Structure of Steptococcus pneumoniae Undecaprenyl pyrophosphate Synthase (UPPS)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0002094molecular_functionpolyprenyltransferase activity
A0004659molecular_functionprenyltransferase activity
A0005515molecular_functionprotein binding
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
A0016094biological_processpolyprenol biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0030145molecular_functionmanganese ion binding
A0033850molecular_functionZ-farnesyl diphosphate synthase activity
A0046872molecular_functionmetal ion binding
B0000287molecular_functionmagnesium ion binding
B0002094molecular_functionpolyprenyltransferase activity
B0004659molecular_functionprenyltransferase activity
B0005515molecular_functionprotein binding
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
B0016094biological_processpolyprenol biosynthetic process
B0016740molecular_functiontransferase activity
B0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
B0030145molecular_functionmanganese ion binding
B0033850molecular_functionZ-farnesyl diphosphate synthase activity
B0046872molecular_functionmetal ion binding
C0000287molecular_functionmagnesium ion binding
C0002094molecular_functionpolyprenyltransferase activity
C0004659molecular_functionprenyltransferase activity
C0005515molecular_functionprotein binding
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
C0016094biological_processpolyprenol biosynthetic process
C0016740molecular_functiontransferase activity
C0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
C0030145molecular_functionmanganese ion binding
C0033850molecular_functionZ-farnesyl diphosphate synthase activity
C0046872molecular_functionmetal ion binding
D0000287molecular_functionmagnesium ion binding
D0002094molecular_functionpolyprenyltransferase activity
D0004659molecular_functionprenyltransferase activity
D0005515molecular_functionprotein binding
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
D0016094biological_processpolyprenol biosynthetic process
D0016740molecular_functiontransferase activity
D0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
D0030145molecular_functionmanganese ion binding
D0033850molecular_functionZ-farnesyl diphosphate synthase activity
D0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS01066
Number of Residues18
DetailsUPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. DLIIRTSGelRlSnFLPW
ChainResidueDetails
AASP196-TRP213

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01139
ChainResidueDetails
AASP28
BASP28
CASP28
DASP28

site_idSWS_FT_FI2
Number of Residues4
DetailsACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01139
ChainResidueDetails
AASN76
BASN76
CASN76
DASN76

site_idSWS_FT_FI3
Number of Residues44
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01139
ChainResidueDetails
AASP28
AARG206
AGLU219
BASP28
BGLY29
BTRP33
BARG41
BHIS45
BSER73
BTRP77
BARG79
AGLY29
BARG200
BARG206
BGLU219
CASP28
CGLY29
CTRP33
CARG41
CHIS45
CSER73
CTRP77
ATRP33
CARG79
CARG200
CARG206
CGLU219
DASP28
DGLY29
DTRP33
DARG41
DHIS45
DSER73
AARG41
DTRP77
DARG79
DARG200
DARG206
DGLU219
AHIS45
ASER73
ATRP77
AARG79
AARG200

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PDB entries from 2024-04-24

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