5KFH

Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 90s

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue MN A 501

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	CA502
A	MN503
A	DTP508
P	DT8
P	DA9
P	HOH214

---

site_id	AC2
Number of Residues	7
Details	binding site for residue CA A 502

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MN501
A	DTP508
A	DPO509
P	DA9

---

site_id	AC3
Number of Residues	7
Details	binding site for residue MN A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MN501
A	DTP508
A	DPO509
P	DA9

---

site_id	AC4
Number of Residues	10
Details	binding site for residue GOL A 504

Chain	Residue
A	ARG24
A	PRO244
A	PHE247
A	SER248
A	GLY276
A	GLU277
A	HOH655
A	HOH663
A	HOH794
A	HOH807

---

site_id	AC5
Number of Residues	9
Details	binding site for residue GOL A 505

Chain	Residue
A	GLU94
A	ALA95
A	GLU98
A	ARG303
A	HOH639
A	HOH676
A	HOH711
A	HOH746
A	HOH823

---

site_id	AC6
Number of Residues	9
Details	binding site for residue GOL A 506

Chain	Residue
A	ASN26
A	PRO27
A	HIS28
A	GLY271
A	GLU273
A	TYR274
A	GLU277
A	HOH616
A	HOH671

---

site_id	AC7
Number of Residues	13
Details	binding site for residue GOL A 507

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	TYR52
A	SER213
A	CYS227
A	GLY228
A	LYS231
A	DTP508
A	DPO509
A	HOH610
A	HOH721
A	HOH766

---

site_id	AC8
Number of Residues	34
Details	binding site for residue DTP A 508

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ILE114
A	ASP115
A	LYS231
A	MN501
A	CA502
A	MN503
A	GOL507
A	DPO509
A	HOH622
A	HOH654
A	HOH695
A	HOH721
A	HOH844
P	DT8
P	DA9
P	MN101
P	HOH202
P	HOH211
P	HOH214
P	HOH216
T	DT3
T	DT4
T	DA5

---

site_id	AC9
Number of Residues	20
Details	binding site for residue DPO A 509

Chain	Residue
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	CA502
A	MN503
A	GOL507
A	DTP508
A	HOH622
A	HOH654
A	HOH721
A	HOH844
P	DA9
P	MN101
A	ASP13

---

site_id	AD1
Number of Residues	8
Details	binding site for residue MN P 101

Chain	Residue
A	ARG61
A	DTP508
A	DPO509
A	HOH622
A	HOH695
A	HOH721
A	HOH844
P	DA9

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO

Chain	Residue	Details
A	ASP13
A	MET14
A	ASP115
A	GLU116

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197

Chain	Residue	Details
A	ARG61

---