5KDV

IMPa metallopeptidase from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
A	0015628	biological_process	protein secretion by the type II secretion system
A	0030163	biological_process	protein catabolic process
A	0043952	biological_process	protein transport by the Sec complex
A	0046872	molecular_function	metal ion binding
A	1903237	biological_process	negative regulation of leukocyte tethering or rolling

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 A 1001

Chain	Residue
A	TYR776
A	HIS927
A	HIS929
A	HIS930
A	HOH1162
A	HOH1231
A	HOH1412

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 1002

Chain	Residue
A	SER286
A	SER287
A	HOH1204
A	ARG283
A	PRO285

---

site_id	AC3
Number of Residues	3
Details	binding site for residue ZN A 1003

Chain	Residue
A	HIS696
A	HIS700
A	GLU716

---

site_id	AC4
Number of Residues	8
Details	binding site for residue EDO A 1004

Chain	Residue
A	SER476
A	LEU477
A	ALA478
A	LYS509
A	VAL529
A	TYR530
A	SER531
A	HOH1641

---

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO A 1005

Chain	Residue
A	ASN225
A	ASN252
A	LYS826
A	THR833
A	HOH1284
A	HOH1515

---

site_id	AC6
Number of Residues	6
Details	binding site for residue EDO A 1006

Chain	Residue
A	ASP186
A	THR251
A	HOH1176
A	HOH1448
A	HOH1491
A	HOH1517

---

site_id	AC7
Number of Residues	5
Details	binding site for residue EDO A 1007

Chain	Residue
A	VAL182
A	LYS187
A	CYS206
A	GLY888
A	HOH1259

---

site_id	AC8
Number of Residues	9
Details	binding site for residue EDO A 1008

Chain	Residue
A	ASP740
A	THR741
A	VAL743
A	ASN900
A	ARG901
A	THR902
A	HOH1166
A	HOH1419
A	HOH1563

---

site_id	AC9
Number of Residues	7
Details	binding site for residue EDO A 1009

Chain	Residue
A	TRP685
A	PRO923
A	LEU924
A	GLU925
A	HIS926
A	HOH1286
A	HOH1428

---

site_id	AD1
Number of Residues	7
Details	binding site for residue EDO A 1010

Chain	Residue
A	THR636
A	ALA638
A	LEU801
A	GLN802
A	ASP805
A	HOH1426
A	HOH1458

---

site_id	AD2
Number of Residues	4
Details	binding site for residue EDO A 1011

Chain	Residue
A	ASP795
A	LEU910
A	HOH1217
A	HOH1411

---

site_id	AD3
Number of Residues	5
Details	binding site for residue EDO A 1012

Chain	Residue
A	SER598
A	TRP685
A	ASN688
A	HIS926
A	HOH1114

---

site_id	AD4
Number of Residues	4
Details	binding site for residue EDO A 1013

Chain	Residue
A	GLN270
A	ALA355
A	LYS359
A	GLN361

---

site_id	AD5
Number of Residues	4
Details	binding site for residue EDO A 1014

Chain	Residue
A	GLU642
A	LEU796
A	LYS797
A	LEU860

---

site_id	AD6
Number of Residues	5
Details	binding site for residue EDO A 1015

Chain	Residue
A	GLN814
A	ASP818
A	ASN840
A	HOH1168
A	HOH1177

---

site_id	AD7
Number of Residues	4
Details	binding site for residue EDO A 1016

Chain	Residue
A	GLN474
A	SER652
A	GLU653
A	THR654

---

site_id	AD8
Number of Residues	4
Details	binding site for residue EDO A 1017

Chain	Residue
A	ARG387
A	TYR388
A	GLU421
A	HOH1545

---

site_id	AD9
Number of Residues	7
Details	binding site for residue EDO A 1018

Chain	Residue
A	HOH1607
A	ARG866
A	PHE869
A	ILE874
A	ARG875
A	THR876
A	GLN881

---

site_id	AE1
Number of Residues	7
Details	binding site for residue EDO A 1019

Chain	Residue
A	GLU439
A	SER466
A	ARG468
A	SER515
A	LYS542
A	VAL543
A	THR544

---

site_id	AE2
Number of Residues	4
Details	binding site for residue EDO A 1020

Chain	Residue
A	GLY351
A	ALA355
A	GLN358
A	HOH1163

---

site_id	AE3
Number of Residues	3
Details	binding site for residue EDO A 1021

Chain	Residue
A	ARG160
A	GLY171
A	HOH1687

---

site_id	AE4
Number of Residues	3
Details	binding site for residue EDO A 1022

Chain	Residue
A	ALA794
A	ASP795
A	ASP799

---

site_id	AE5
Number of Residues	5
Details	binding site for residue EDO A 1023

Chain	Residue
A	ASP120
A	ARG292
A	HOH1135
A	HOH1203
A	HOH1699

---

site_id	AE6
Number of Residues	5
Details	binding site for residue EDO A 1024

Chain	Residue
A	ASN750
A	ALA919
A	TRP920
A	HOH1388
A	HOH1635

---

site_id	AE7
Number of Residues	6
Details	binding site for residue EDO A 1025

Chain	Residue
A	ASN357
A	GLN361
A	ASN362
A	LEU363
A	GLY410
A	VAL412

---

site_id	AE8
Number of Residues	4
Details	binding site for residue EDO A 1026

Chain	Residue
A	ASP186
A	LYS187
A	THR188
A	HOH1490

---

site_id	AE9
Number of Residues	7
Details	binding site for residue EDO A 1027

Chain	Residue
A	TYR710
A	ARG713
A	ASN766
A	TRP770
A	ALA844
A	HOH1205
A	HOH1493

---

site_id	AF1
Number of Residues	3
Details	binding site for residue EDO A 1028

Chain	Residue
A	GLY427
A	GLN428
A	HOH1327

---

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. GESHELGHNL

Chain	Residue	Details
A	GLY693-LEU702

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
A	GLU697

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
A	HIS696
A	HIS700

---