5KBX
Co-crystal structure of the Saccharomyces cerevisiae histidine phosphotransfer signaling protein Ypd1 and the receiver domain of its downstream response regulator Ssk1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000160 | biological_process | phosphorelay signal transduction system |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0007234 | biological_process | osmosensory signaling via phosphorelay pathway |
| A | 0009927 | molecular_function | histidine phosphotransfer kinase activity |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0043424 | molecular_function | protein histidine kinase binding |
| B | 0000160 | biological_process | phosphorelay signal transduction system |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 201 |
| Chain | Residue |
| A | TRP11 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 202 |
| Chain | Residue |
| A | HIS64 |
| A | LYS67 |
| A | GLN86 |
| B | GLN556 |
| B | ALA611 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue GOL B 801 |
| Chain | Residue |
| B | PO4803 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 802 |
| Chain | Residue |
| B | HIS637 |
| B | SER640 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 B 803 |
| Chain | Residue |
| B | LYS641 |
| B | LYS642 |
| B | GLU645 |
| B | GOL801 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: 4-aspartylphosphate => ECO:0000255|PROSITE-ProRule:PRU00169, ECO:0000269|PubMed:8808622 |
| Chain | Residue | Details |
| B | ASP554 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:17330950 |
| Chain | Residue | Details |
| B | SER673 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17287358 |
| Chain | Residue | Details |
| B | THR693 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| B | SER703 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| B | SER706 |
