Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003933 | molecular_function | GTP cyclohydrolase activity |
| A | 0003934 | molecular_function | GTP cyclohydrolase I activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0003933 | molecular_function | GTP cyclohydrolase activity |
| B | 0003934 | molecular_function | GTP cyclohydrolase I activity |
| B | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | CYS147 |
| A | HIS159 |
| A | GLU201 |
| A | HOH474 |
| A | HOH530 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | SER171 |
| A | GLU174 |
| A | VAL175 |
| A | PHE76 |
| A | HIS135 |
| A | SER136 |
| A | LEU169 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 303 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 301 |
| Chain | Residue |
| B | CYS147 |
| B | HIS159 |
| B | GLU201 |
| B | TRS302 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue TRS B 302 |
| Chain | Residue |
| A | MET60 |
| B | CYS147 |
| B | HIS159 |
| B | GLU201 |
| B | GLU243 |
| B | HIS246 |
| B | ZN301 |
| B | HOH405 |
| B | HOH433 |
| B | HOH535 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | PHE76 |
| B | HIS135 |
| B | SER136 |
| B | MET137 |
| B | LEU169 |
| B | SER171 |
| B | VAL175 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | SER168 |
| B | LEU169 |
| B | THR170 |
| B | SER234 |
| B | PHE235 |
| B | HOH541 |
| B | HOH589 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | LYS107 |
| B | THR108 |
| B | GLN191 |
| B | TYR193 |
| B | HOH517 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | THR125 |
| B | GLU127 |
| B | GLY134 |
| B | SER136 |
| B | THR170 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | LYS151 |
| B | TYR156 |
| B | TYR209 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| B | LYS33 |
| B | THR34 |
| B | PHE76 |
| B | GLY176 |
| B | ILE177 |
| B | HOH417 |
| B | HOH459 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 309 |
| Chain | Residue |
| B | CYS147 |
| B | HIS159 |
| B | GLN161 |
| B | ASN241 |
| B | GLU243 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: May be catalytically important => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS147 | |
| B | CYS147 | |
