5K98

Structure of HipA-HipB-O2-O3 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001217	molecular_function	DNA-binding transcription repressor activity
A	0003677	molecular_function	DNA binding
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006355	biological_process	regulation of DNA-templated transcription
A	0022611	biological_process	dormancy process
A	0032993	cellular_component	protein-DNA complex
A	0040008	biological_process	regulation of growth
A	0043565	molecular_function	sequence-specific DNA binding
A	0044010	biological_process	single-species biofilm formation
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0046677	biological_process	response to antibiotic
A	0106310	molecular_function	protein serine kinase activity
A	0110001	cellular_component	toxin-antitoxin complex
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0001046	molecular_function	core promoter sequence-specific DNA binding
B	0001217	molecular_function	DNA-binding transcription repressor activity
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0032993	cellular_component	protein-DNA complex
B	0040008	biological_process	regulation of growth
B	0042803	molecular_function	protein homodimerization activity
B	0043565	molecular_function	sequence-specific DNA binding
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0110001	cellular_component	toxin-antitoxin complex
D	0000287	molecular_function	magnesium ion binding
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0001217	molecular_function	DNA-binding transcription repressor activity
D	0003677	molecular_function	DNA binding
D	0004674	molecular_function	protein serine/threonine kinase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005829	cellular_component	cytosol
D	0006355	biological_process	regulation of DNA-templated transcription
D	0022611	biological_process	dormancy process
D	0032993	cellular_component	protein-DNA complex
D	0040008	biological_process	regulation of growth
D	0043565	molecular_function	sequence-specific DNA binding
D	0044010	biological_process	single-species biofilm formation
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0046677	biological_process	response to antibiotic
D	0106310	molecular_function	protein serine kinase activity
D	0110001	cellular_component	toxin-antitoxin complex
P	0000976	molecular_function	transcription cis-regulatory region binding
P	0001046	molecular_function	core promoter sequence-specific DNA binding
P	0001217	molecular_function	DNA-binding transcription repressor activity
P	0003677	molecular_function	DNA binding
P	0005515	molecular_function	protein binding
P	0006351	biological_process	DNA-templated transcription
P	0006355	biological_process	regulation of DNA-templated transcription
P	0032993	cellular_component	protein-DNA complex
P	0040008	biological_process	regulation of growth
P	0042803	molecular_function	protein homodimerization activity
P	0043565	molecular_function	sequence-specific DNA binding
P	0045892	biological_process	negative regulation of DNA-templated transcription
P	0110001	cellular_component	toxin-antitoxin complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	52
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00257, ECO:0000269|PubMed:19150849

Chain	Residue	Details
B	ARG21-ASN47
P	ARG21-ASN47

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:17041039

Chain	Residue	Details
A	GLN309
D	GLN309

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:22999936, ECO:0007744|PDB:3DNT, ECO:0007744|PDB:3FBR, ECO:0007744|PDB:3HZI, ECO:0007744|PDB:3TPT

Chain	Residue	Details
A	ALA152
A	GLU234
A	HIS311
A	TYR331
D	ALA152
D	GLU234
D	HIS311
D	TYR331

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site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:22999936, ECO:0007744|PDB:3DNT, ECO:0007744|PDB:3HZI, ECO:0007744|PDB:3TPT

Chain	Residue	Details
A	LYS181
D	LYS181

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphoserine; by autocatalysis => ECO:0000269|PubMed:17041039, ECO:0000269|PubMed:22999936

Chain	Residue	Details
A	SER150
D	SER150

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