Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5K3H

Crystals structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans, Apo form-II

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003997	molecular_function	acyl-CoA oxidase activity
A	0005504	molecular_function	fatty acid binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0006631	biological_process	fatty acid metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0009058	biological_process	biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
A	0042811	biological_process	pheromone biosynthetic process
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0055088	biological_process	lipid homeostasis
A	0071949	molecular_function	FAD binding
A	1904070	biological_process	ascaroside biosynthetic process
B	0003997	molecular_function	acyl-CoA oxidase activity
B	0005504	molecular_function	fatty acid binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005777	cellular_component	peroxisome
B	0005782	cellular_component	peroxisomal matrix
B	0006631	biological_process	fatty acid metabolic process
B	0006635	biological_process	fatty acid beta-oxidation
B	0009058	biological_process	biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
B	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
B	0042811	biological_process	pheromone biosynthetic process
B	0050660	molecular_function	flavin adenine dinucleotide binding
B	0055088	biological_process	lipid homeostasis
B	0071949	molecular_function	FAD binding
B	1904070	biological_process	ascaroside biosynthetic process
C	0003997	molecular_function	acyl-CoA oxidase activity
C	0005504	molecular_function	fatty acid binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005777	cellular_component	peroxisome
C	0005782	cellular_component	peroxisomal matrix
C	0006631	biological_process	fatty acid metabolic process
C	0006635	biological_process	fatty acid beta-oxidation
C	0009058	biological_process	biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
C	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
C	0042811	biological_process	pheromone biosynthetic process
C	0050660	molecular_function	flavin adenine dinucleotide binding
C	0055088	biological_process	lipid homeostasis
C	0071949	molecular_function	FAD binding
C	1904070	biological_process	ascaroside biosynthetic process
D	0003997	molecular_function	acyl-CoA oxidase activity
D	0005504	molecular_function	fatty acid binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005777	cellular_component	peroxisome
D	0005782	cellular_component	peroxisomal matrix
D	0006631	biological_process	fatty acid metabolic process
D	0006635	biological_process	fatty acid beta-oxidation
D	0009058	biological_process	biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
D	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
D	0042811	biological_process	pheromone biosynthetic process
D	0050660	molecular_function	flavin adenine dinucleotide binding
D	0055088	biological_process	lipid homeostasis
D	0071949	molecular_function	FAD binding
D	1904070	biological_process	ascaroside biosynthetic process
E	0003997	molecular_function	acyl-CoA oxidase activity
E	0005504	molecular_function	fatty acid binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005777	cellular_component	peroxisome
E	0005782	cellular_component	peroxisomal matrix
E	0006631	biological_process	fatty acid metabolic process
E	0006635	biological_process	fatty acid beta-oxidation
E	0009058	biological_process	biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
E	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
E	0042811	biological_process	pheromone biosynthetic process
E	0050660	molecular_function	flavin adenine dinucleotide binding
E	0055088	biological_process	lipid homeostasis
E	0071949	molecular_function	FAD binding
E	1904070	biological_process	ascaroside biosynthetic process
F	0003997	molecular_function	acyl-CoA oxidase activity
F	0005504	molecular_function	fatty acid binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005777	cellular_component	peroxisome
F	0005782	cellular_component	peroxisomal matrix
F	0006631	biological_process	fatty acid metabolic process
F	0006635	biological_process	fatty acid beta-oxidation
F	0009058	biological_process	biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
F	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
F	0042811	biological_process	pheromone biosynthetic process
F	0050660	molecular_function	flavin adenine dinucleotide binding
F	0055088	biological_process	lipid homeostasis
F	0071949	molecular_function	FAD binding
F	1904070	biological_process	ascaroside biosynthetic process
G	0003997	molecular_function	acyl-CoA oxidase activity
G	0005504	molecular_function	fatty acid binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005777	cellular_component	peroxisome
G	0005782	cellular_component	peroxisomal matrix
G	0006631	biological_process	fatty acid metabolic process
G	0006635	biological_process	fatty acid beta-oxidation
G	0009058	biological_process	biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
G	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
G	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
G	0042811	biological_process	pheromone biosynthetic process
G	0050660	molecular_function	flavin adenine dinucleotide binding
G	0055088	biological_process	lipid homeostasis
G	0071949	molecular_function	FAD binding
G	1904070	biological_process	ascaroside biosynthetic process
H	0003997	molecular_function	acyl-CoA oxidase activity
H	0005504	molecular_function	fatty acid binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005777	cellular_component	peroxisome
H	0005782	cellular_component	peroxisomal matrix
H	0006631	biological_process	fatty acid metabolic process
H	0006635	biological_process	fatty acid beta-oxidation
H	0009058	biological_process	biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
H	0033540	biological_process	fatty acid beta-oxidation using acyl-CoA oxidase
H	0042811	biological_process	pheromone biosynthetic process
H	0050660	molecular_function	flavin adenine dinucleotide binding
H	0055088	biological_process	lipid homeostasis
H	0071949	molecular_function	FAD binding
H	1904070	biological_process	ascaroside biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000255\|PIRSR:PIRSR000168-1

Chain	Residue	Details
A	GLU434
B	GLU434
C	GLU434
D	GLU434
E	GLU434
F	GLU434
G	GLU434
H	GLU434

site_id	SWS_FT_FI2
Number of Residues	48
Details	BINDING: in other chain => ECO:0000269\|PubMed:27551084, ECO:0007744\|PDB:5K3I

Chain	Residue	Details
A	TYR149
B	HIS396
B	ARG533
B	TYR581
C	TYR149
C	GLY157
C	SER392
C	HIS396
C	ARG533
C	TYR581
D	TYR149
A	GLY157
D	GLY157
D	SER392
D	HIS396
D	ARG533
D	TYR581
E	TYR149
E	GLY157
E	SER392
E	HIS396
E	ARG533
A	SER392
E	TYR581
F	TYR149
F	GLY157
F	SER392
F	HIS396
F	ARG533
F	TYR581
G	TYR149
G	GLY157
G	SER392
A	HIS396
G	HIS396
G	ARG533
G	TYR581
H	TYR149
H	GLY157
H	SER392
H	HIS396
H	ARG533
H	TYR581
A	ARG533
A	TYR581
B	TYR149
B	GLY157
B	SER392

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: in other chain => ECO:0000255\|PIRSR:PIRSR000168-2, ECO:0000269\|PubMed:27551084, ECO:0007744\|PDB:5K3I

Chain	Residue	Details
A	GLY191
B	GLY191
C	GLY191
D	GLY191
E	GLY191
F	GLY191
G	GLY191
H	GLY191

site_id	SWS_FT_FI4
Number of Residues	40
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:O62137

Chain	Residue	Details
A	LYS285
B	TYR433
C	LYS285
C	ARG295
C	HIS342
C	GLY411
C	TYR433
D	LYS285
D	ARG295
D	HIS342
D	GLY411
A	ARG295
D	TYR433
E	LYS285
E	ARG295
E	HIS342
E	GLY411
E	TYR433
F	LYS285
F	ARG295
F	HIS342
F	GLY411
A	HIS342
F	TYR433
G	LYS285
G	ARG295
G	HIS342
G	GLY411
G	TYR433
H	LYS285
H	ARG295
H	HIS342
H	GLY411
A	GLY411
H	TYR433
A	TYR433
B	LYS285
B	ARG295
B	HIS342
B	GLY411

site_id	SWS_FT_FI5
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269\|PubMed:27551084, ECO:0007744\|PDB:5K3I

Chain	Residue	Details
A	ARG320
D	ARG320
D	GLN340
D	GLN404
E	ARG320
E	GLN340
E	GLN404
F	ARG320
F	GLN340
F	GLN404
G	ARG320
A	GLN340
G	GLN340
G	GLN404
H	ARG320
H	GLN340
H	GLN404
A	GLN404
B	ARG320
B	GLN340
B	GLN404
C	ARG320
C	GLN340
C	GLN404

site_id	SWS_FT_FI6
Number of Residues	8
Details	BINDING: in other chain => ECO:0000250\|UniProtKB:O62137

Chain	Residue	Details
A	GLU436
B	GLU436
C	GLU436
D	GLU436
E	GLU436
F	GLU436
G	GLU436
H	GLU436

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)