Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5JYD

Crystal Structure of a Putative Short Chain Dehydrogenase from Burkholderia cenocepacia

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
B	0016491	molecular_function	oxidoreductase activity
C	0016491	molecular_function	oxidoreductase activity
D	0016491	molecular_function	oxidoreductase activity
E	0016491	molecular_function	oxidoreductase activity
F	0016491	molecular_function	oxidoreductase activity
G	0016491	molecular_function	oxidoreductase activity
H	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	36
Details	binding site for residue NAD A 901

Chain	Residue
A	GLY76
A	ASP128
A	ILE129
A	ASN155
A	ALA156
A	ALA157
A	THR204
A	THR205
A	SER206
A	TYR219
A	LYS223
A	ASP78
A	PRO249
A	GLY250
A	PRO251
A	TYR252
A	THR254
A	PRO255
A	LEU256
A	GLN257
A	TYR270
A	MG902
A	SER79
A	HOH1006
A	HOH1011
A	HOH1049
A	HOH1072
A	HOH1091
A	HOH1175
A	HOH1191
A	GLY80
A	ILE81
A	TYR100
A	LEU101
A	GLU104
A	GLY127

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 902

Chain	Residue
A	ASP78
A	SER79
A	GLU104
A	NAD901
A	HOH1011
A	HOH1052

site_id	AC3
Number of Residues	1
Details	binding site for residue IOD A 903

Chain	Residue
A	VAL207

site_id	AC4
Number of Residues	1
Details	binding site for residue IOD A 908

Chain	Residue
A	ARG83

site_id	AC5
Number of Residues	5
Details	binding site for residue NA A 910

Chain	Residue
A	VAL304
A	PHE314
B	VAL304
B	PHE314
B	HOH1204

site_id	AC6
Number of Residues	35
Details	binding site for residue NAD B 901

Chain	Residue
B	GLY76
B	ASP78
B	SER79
B	GLY80
B	ILE81
B	TYR100
B	LEU101
B	GLU104
B	GLY127
B	ASP128
B	ILE129
B	ASN155
B	ALA156
B	ALA157
B	THR204
B	THR205
B	SER206
B	TYR219
B	LYS223
B	PRO249
B	GLY250
B	PRO251
B	TYR252
B	THR254
B	PRO255
B	LEU256
B	GLN257
B	TYR270
B	MG902
B	HOH1036
B	HOH1045
B	HOH1091
B	HOH1104
B	HOH1122
B	HOH1160

site_id	AC7
Number of Residues	6
Details	binding site for residue MG B 902

Chain	Residue
B	ASP78
B	SER79
B	GLU104
B	NAD901
B	HOH1013
B	HOH1036

site_id	AC8
Number of Residues	1
Details	binding site for residue IOD B 904

Chain	Residue
B	ARG83

site_id	AC9
Number of Residues	1
Details	binding site for residue IOD B 906

Chain	Residue
B	VAL207

site_id	AD1
Number of Residues	1
Details	binding site for residue IOD B 909

Chain	Residue
B	GLY63

site_id	AD2
Number of Residues	35
Details	binding site for residue NAD C 901

Chain	Residue
C	LEU101
C	GLU104
C	GLY127
C	ASP128
C	ILE129
C	ASN155
C	ALA156
C	ALA157
C	THR179
C	THR204
C	THR205
C	SER206
C	TYR219
C	LYS223
C	PRO249
C	GLY250
C	PRO251
C	TYR252
C	THR254
C	PRO255
C	LEU256
C	GLN257
C	TYR270
C	MG902
C	HOH1025
C	HOH1082
C	HOH1092
C	HOH1143
C	HOH1211
C	GLY76
C	ASP78
C	SER79
C	GLY80
C	ILE81
C	TYR100

site_id	AD3
Number of Residues	6
Details	binding site for residue MG C 902

Chain	Residue
C	ASP78
C	SER79
C	GLU104
C	NAD901
C	HOH1025
C	HOH1040

site_id	AD4
Number of Residues	1
Details	binding site for residue IOD C 904

Chain	Residue
C	VAL207

site_id	AD5
Number of Residues	1
Details	binding site for residue IOD C 906

Chain	Residue
C	ARG83

site_id	AD6
Number of Residues	5
Details	binding site for residue NA C 909

Chain	Residue
C	VAL304
C	PHE314
D	VAL304
D	PHE314
D	HOH1252

site_id	AD7
Number of Residues	35
Details	binding site for residue NAD D 901

Chain	Residue
D	GLY76
D	ASP78
D	SER79
D	GLY80
D	ILE81
D	TYR100
D	LEU101
D	GLU104
D	GLY127
D	ASP128
D	ILE129
D	ASN155
D	ALA156
D	ALA157
D	THR179
D	THR204
D	THR205
D	SER206
D	TYR219
D	LYS223
D	PRO249
D	GLY250
D	PRO251
D	TYR252
D	THR254
D	PRO255
D	LEU256
D	GLN257
D	TYR270
D	MG902
D	HOH1031
D	HOH1119
D	HOH1126
D	HOH1139
D	HOH1209

site_id	AD8
Number of Residues	6
Details	binding site for residue MG D 902

Chain	Residue
D	ASP78
D	SER79
D	GLU104
D	NAD901
D	HOH1019
D	HOH1031

site_id	AD9
Number of Residues	1
Details	binding site for residue IOD D 905

Chain	Residue
D	HOH1203

site_id	AE1
Number of Residues	1
Details	binding site for residue IOD D 908

Chain	Residue
D	VAL207

site_id	AE2
Number of Residues	6
Details	binding site for residue EDO D 910

Chain	Residue
B	SER164
B	GLY166
D	ILE192
D	ARG240
D	HOH1002
D	HOH1034

site_id	AE3
Number of Residues	8
Details	binding site for residue EDO D 911

Chain	Residue
B	ILE192
B	ARG240
B	HOH1193
D	SER164
D	GLY166
D	HOH1001
D	HOH1010
D	HOH1085

site_id	AE4
Number of Residues	34
Details	binding site for residue NAD E 901

Chain	Residue
E	ASP78
E	SER79
E	GLY80
E	ILE81
E	TYR100
E	LEU101
E	GLU104
E	GLY127
E	ASP128
E	ILE129
E	ASN155
E	ALA156
E	ALA157
E	THR204
E	THR205
E	SER206
E	TYR219
E	LYS223
E	PRO249
E	GLY250
E	PRO251
E	TYR252
E	THR254
E	PRO255
E	LEU256
E	GLN257
E	TYR270
E	MG902
E	HOH1022
E	HOH1050
E	HOH1095
E	HOH1129
E	HOH1191
E	HOH1193

site_id	AE5
Number of Residues	6
Details	binding site for residue MG E 902

Chain	Residue
E	ASP78
E	SER79
E	GLU104
E	NAD901
E	HOH1011
E	HOH1022

site_id	AE6
Number of Residues	1
Details	binding site for residue IOD E 903

Chain	Residue
E	ARG83

site_id	AE7
Number of Residues	2
Details	binding site for residue IOD E 904

Chain	Residue
E	GLY63
E	HOH1268

site_id	AE8
Number of Residues	1
Details	binding site for residue IOD E 910

Chain	Residue
E	VAL207

site_id	AE9
Number of Residues	7
Details	binding site for residue EDO E 911

Chain	Residue
E	SER164
E	ILE165
E	GLY166
E	HOH1112
E	HOH1135
G	ILE192
G	HOH1097

site_id	AF1
Number of Residues	6
Details	binding site for residue EDO E 912

Chain	Residue
A	THR169
E	ASP174
E	HOH1001
E	HOH1143
G	TRP186
G	HOH1128

site_id	AF2
Number of Residues	5
Details	binding site for residue NA E 913

Chain	Residue
E	VAL304
E	PHE314
F	VAL304
F	PHE314
F	HOH1170

site_id	AF3
Number of Residues	33
Details	binding site for residue NAD F 901

Chain	Residue
F	ASP78
F	SER79
F	GLY80
F	ILE81
F	TYR100
F	LEU101
F	GLU104
F	GLY127
F	ASP128
F	ILE129
F	ASN155
F	ALA156
F	ALA157
F	THR204
F	THR205
F	SER206
F	TYR219
F	LYS223
F	PRO249
F	GLY250
F	PRO251
F	TYR252
F	THR254
F	PRO255
F	LEU256
F	GLN257
F	TYR270
F	MG902
F	HOH1031
F	HOH1043
F	HOH1058
F	HOH1072
F	HOH1142

site_id	AF4
Number of Residues	6
Details	binding site for residue MG F 902

Chain	Residue
F	ASP78
F	SER79
F	GLU104
F	NAD901
F	HOH1031
F	HOH1036

site_id	AF5
Number of Residues	1
Details	binding site for residue IOD F 905

Chain	Residue
F	VAL207

site_id	AF6
Number of Residues	1
Details	binding site for residue IOD F 907

Chain	Residue
F	ARG83

site_id	AF7
Number of Residues	1
Details	binding site for residue IOD F 909

Chain	Residue
F	HOH1148

site_id	AF8
Number of Residues	35
Details	binding site for residue NAD G 901

Chain	Residue
G	GLY76
G	ASP78
G	SER79
G	GLY80
G	ILE81
G	TYR100
G	LEU101
G	GLU104
G	GLY127
G	ASP128
G	ILE129
G	ASN155
G	ALA156
G	ALA157
G	THR179
G	THR204
G	THR205
G	SER206
G	TYR219
G	LYS223
G	PRO249
G	GLY250
G	PRO251
G	TYR252
G	THR254
G	PRO255
G	LEU256
G	GLN257
G	TYR270
G	MG902
G	HOH1015
G	HOH1061
G	HOH1074
G	HOH1139
G	HOH1166

site_id	AF9
Number of Residues	6
Details	binding site for residue MG G 902

Chain	Residue
G	ASP78
G	SER79
G	GLU104
G	NAD901
G	HOH1015
G	HOH1042

site_id	AG1
Number of Residues	1
Details	binding site for residue IOD G 904

Chain	Residue
G	VAL207

site_id	AG2
Number of Residues	1
Details	binding site for residue IOD G 907

Chain	Residue
G	ARG83

site_id	AG3
Number of Residues	1
Details	binding site for residue IOD G 908

Chain	Residue
G	ARG116

site_id	AG4
Number of Residues	4
Details	binding site for residue EDO G 909

Chain	Residue
G	GLN51
G	PRO52
G	HOH1001
G	HOH1124

site_id	AG5
Number of Residues	5
Details	binding site for residue NA G 910

Chain	Residue
G	VAL304
G	PHE314
G	HOH1211
H	VAL304
H	PHE314

site_id	AG6
Number of Residues	34
Details	binding site for residue NAD H 901

Chain	Residue
H	GLY76
H	ASP78
H	SER79
H	GLY80
H	ILE81
H	TYR100
H	LEU101
H	GLU104
H	GLY127
H	ASP128
H	ILE129
H	ASN155
H	ALA156
H	ALA157
H	THR204
H	THR205
H	SER206
H	TYR219
H	LYS223
H	PRO249
H	GLY250
H	PRO251
H	TYR252
H	THR254
H	PRO255
H	LEU256
H	GLN257
H	TYR270
H	MG902
H	HOH1035
H	HOH1046
H	HOH1101
H	HOH1115
H	HOH1141

site_id	AG7
Number of Residues	6
Details	binding site for residue MG H 902

Chain	Residue
H	ASP78
H	SER79
H	GLU104
H	NAD901
H	HOH1009
H	HOH1035

site_id	AG8
Number of Residues	2
Details	binding site for residue IOD H 904

Chain	Residue
H	VAL207
H	ARG211

site_id	AG9
Number of Residues	1
Details	binding site for residue IOD H 905

Chain	Residue
H	ARG211

site_id	AH1
Number of Residues	2
Details	binding site for residues IOD E 907 and IOD G 903

Chain	Residue
E	ARG83
G	ARG83

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvqavrasanLldYATTKAGIiAFTrSLA

Chain	Residue	Details
A	SER206-ALA234

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)