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5JYA

Structures of Streptococcus agalactiae GBS GAPDH in different enzymatic states

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004365molecular_functionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A0006006biological_processglucose metabolic process
A0006096biological_processglycolytic process
A0016491molecular_functionoxidoreductase activity
A0016620molecular_functionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A0042802molecular_functionidentical protein binding
A0046872molecular_functionmetal ion binding
A0050661molecular_functionNADP binding
A0051287molecular_functionNAD binding
B0000166molecular_functionnucleotide binding
B0004365molecular_functionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B0006006biological_processglucose metabolic process
B0006096biological_processglycolytic process
B0016491molecular_functionoxidoreductase activity
B0016620molecular_functionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B0042802molecular_functionidentical protein binding
B0046872molecular_functionmetal ion binding
B0050661molecular_functionNADP binding
B0051287molecular_functionNAD binding
C0000166molecular_functionnucleotide binding
C0004365molecular_functionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0006006biological_processglucose metabolic process
C0006096biological_processglycolytic process
C0016491molecular_functionoxidoreductase activity
C0016620molecular_functionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C0042802molecular_functionidentical protein binding
C0046872molecular_functionmetal ion binding
C0050661molecular_functionNADP binding
C0051287molecular_functionNAD binding
D0000166molecular_functionnucleotide binding
D0004365molecular_functionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0006006biological_processglucose metabolic process
D0006096biological_processglycolytic process
D0016491molecular_functionoxidoreductase activity
D0016620molecular_functionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D0042802molecular_functionidentical protein binding
D0046872molecular_functionmetal ion binding
D0050661molecular_functionNADP binding
D0051287molecular_functionNAD binding
Functional Information from PDB Data
site_idAC1
Number of Residues21
Detailsbinding site for residue NAD A 401
ChainResidue
AGLY9
AGLY98
APHE99
APHE100
ATHR121
AALA122
AASN316
ATYR320
AG3H402
AHOH506
AHOH507
AGLY11
AHOH514
CPRO191
AARG12
AILE13
AASP34
ALEU35
AARG78
AALA96
ATHR97

site_idAC2
Number of Residues10
Detailsbinding site for residue G3H A 402
ChainResidue
ASER151
ASER152
ATHR153
AHIS179
ATHR212
AGLY213
AARG235
ANAD401
AHOH520
AHOH528

site_idAC3
Number of Residues26
Detailsbinding site for residue NAD B 401
ChainResidue
BASN8
BGLY9
BGLY11
BARG12
BILE13
BASP34
BLEU35
BGLU77
BARG78
BALA96
BTHR97
BGLY98
BPHE99
BPHE100
BTHR121
BALA122
BSER152
BASN316
BTYR320
BG3H402
BHOH514
BHOH526
BHOH528
BHOH529
DPRO191
DHOH513

site_idAC4
Number of Residues7
Detailsbinding site for residue G3H B 402
ChainResidue
BSER151
BSER152
BTHR153
BHIS179
BASP184
BGLY213
BNAD401

site_idAC5
Number of Residues22
Detailsbinding site for residue NAD C 401
ChainResidue
APRO191
CASN8
CGLY9
CGLY11
CARG12
CILE13
CASP34
CLEU35
CGLU77
CARG78
CALA96
CTHR97
CGLY98
CPHE99
CTHR121
CALA122
CASN316
CTYR320
CG3H402
CHOH518
CHOH525
CHOH528

site_idAC6
Number of Residues8
Detailsbinding site for residue G3H C 402
ChainResidue
CSER151
CSER152
CTHR153
CHIS179
CTHR212
CGLY213
CNAD401
CHOH533

site_idAC7
Number of Residues23
Detailsbinding site for residue NAD D 401
ChainResidue
DILE13
DASP34
DLEU35
DGLU77
DARG78
DALA96
DTHR97
DGLY98
DPHE99
DTHR121
DALA122
DASN316
DTYR320
DG3H402
DHOH509
DHOH516
DHOH535
DHOH540
BPRO191
BHOH503
DGLY9
DGLY11
DARG12

site_idAC8
Number of Residues7
Detailsbinding site for residue G3H D 402
ChainResidue
DSER151
DSER152
DTHR153
DHIS179
DTHR212
DGLY213
DNAD401

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PDB entries from 2025-12-24

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