5JYA
Structures of Streptococcus agalactiae GBS GAPDH in different enzymatic states
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
| C | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| C | 0006006 | biological_process | glucose metabolic process |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0050661 | molecular_function | NADP binding |
| C | 0051287 | molecular_function | NAD binding |
| D | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| D | 0006006 | biological_process | glucose metabolic process |
| D | 0006096 | biological_process | glycolytic process |
| D | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0050661 | molecular_function | NADP binding |
| D | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | GLY9 |
| A | GLY98 |
| A | PHE99 |
| A | PHE100 |
| A | THR121 |
| A | ALA122 |
| A | ASN316 |
| A | TYR320 |
| A | G3H402 |
| A | HOH506 |
| A | HOH507 |
| A | GLY11 |
| A | HOH514 |
| C | PRO191 |
| A | ARG12 |
| A | ILE13 |
| A | ASP34 |
| A | LEU35 |
| A | ARG78 |
| A | ALA96 |
| A | THR97 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue G3H A 402 |
| Chain | Residue |
| A | SER151 |
| A | SER152 |
| A | THR153 |
| A | HIS179 |
| A | THR212 |
| A | GLY213 |
| A | ARG235 |
| A | NAD401 |
| A | HOH520 |
| A | HOH528 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | binding site for residue NAD B 401 |
| Chain | Residue |
| B | ASN8 |
| B | GLY9 |
| B | GLY11 |
| B | ARG12 |
| B | ILE13 |
| B | ASP34 |
| B | LEU35 |
| B | GLU77 |
| B | ARG78 |
| B | ALA96 |
| B | THR97 |
| B | GLY98 |
| B | PHE99 |
| B | PHE100 |
| B | THR121 |
| B | ALA122 |
| B | SER152 |
| B | ASN316 |
| B | TYR320 |
| B | G3H402 |
| B | HOH514 |
| B | HOH526 |
| B | HOH528 |
| B | HOH529 |
| D | PRO191 |
| D | HOH513 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue G3H B 402 |
| Chain | Residue |
| B | SER151 |
| B | SER152 |
| B | THR153 |
| B | HIS179 |
| B | ASP184 |
| B | GLY213 |
| B | NAD401 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | binding site for residue NAD C 401 |
| Chain | Residue |
| A | PRO191 |
| C | ASN8 |
| C | GLY9 |
| C | GLY11 |
| C | ARG12 |
| C | ILE13 |
| C | ASP34 |
| C | LEU35 |
| C | GLU77 |
| C | ARG78 |
| C | ALA96 |
| C | THR97 |
| C | GLY98 |
| C | PHE99 |
| C | THR121 |
| C | ALA122 |
| C | ASN316 |
| C | TYR320 |
| C | G3H402 |
| C | HOH518 |
| C | HOH525 |
| C | HOH528 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue G3H C 402 |
| Chain | Residue |
| C | SER151 |
| C | SER152 |
| C | THR153 |
| C | HIS179 |
| C | THR212 |
| C | GLY213 |
| C | NAD401 |
| C | HOH533 |
| site_id | AC7 |
| Number of Residues | 23 |
| Details | binding site for residue NAD D 401 |
| Chain | Residue |
| D | ILE13 |
| D | ASP34 |
| D | LEU35 |
| D | GLU77 |
| D | ARG78 |
| D | ALA96 |
| D | THR97 |
| D | GLY98 |
| D | PHE99 |
| D | THR121 |
| D | ALA122 |
| D | ASN316 |
| D | TYR320 |
| D | G3H402 |
| D | HOH509 |
| D | HOH516 |
| D | HOH535 |
| D | HOH540 |
| B | PRO191 |
| B | HOH503 |
| D | GLY9 |
| D | GLY11 |
| D | ARG12 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue G3H D 402 |
| Chain | Residue |
| D | SER151 |
| D | SER152 |
| D | THR153 |
| D | HIS179 |
| D | THR212 |
| D | GLY213 |
| D | NAD401 |
