5JX0
Temperature sensitive D4 mutant L110F
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| C | 0006281 | biological_process | DNA repair |
| C | 0006974 | biological_process | DNA damage response |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| D | 0006281 | biological_process | DNA repair |
| D | 0006974 | biological_process | DNA damage response |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | GLY66 |
| A | ASP68 |
| A | TYR70 |
| A | PRO78 |
| A | PHE79 |
| A | ASN120 |
| A | HOH404 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 302 |
| Chain | Residue |
| A | LYS160 |
| A | HIS181 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| B | GLY66 |
| B | ASP68 |
| B | PRO69 |
| B | PHE79 |
| B | SER88 |
| B | ASN120 |
| B | HIS181 |
| B | HOH410 |
| B | HOH433 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 302 |
| Chain | Residue |
| B | LYS160 |
| B | HIS181 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | GLY66 |
| C | ILE67 |
| C | ASP68 |
| C | PRO69 |
| C | TYR70 |
| C | PHE79 |
| C | ASN120 |
| C | HOH404 |
| C | HOH414 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 302 |
| Chain | Residue |
| C | LYS160 |
| C | HIS181 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| D | GLY66 |
| D | ASP68 |
| D | PRO69 |
| D | TYR70 |
| D | PHE79 |
| D | ASN120 |
| D | HOH409 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue CL D 302 |
| Chain | Residue |
| D | LYS160 |
| D | HIS181 |
Functional Information from PROSITE/UniProt
| site_id | PS00130 |
| Number of Residues | 10 |
| Details | U_DNA_GLYCOSYLASE Uracil-DNA glycosylase signature. RVCVcGIDPY |
| Chain | Residue | Details |
| A | ARG61-TYR70 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10072","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
