5JWY
Structure of lipid phosphate phosphatase PgpB complex with PE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000810 | molecular_function | diacylglycerol diphosphate phosphatase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006655 | biological_process | phosphatidylglycerol biosynthetic process |
| A | 0008195 | molecular_function | phosphatidate phosphatase activity |
| A | 0008962 | molecular_function | phosphatidylglycerophosphatase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0009279 | cellular_component | cell outer membrane |
| A | 0009395 | biological_process | phospholipid catabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046474 | biological_process | glycerophospholipid biosynthetic process |
| A | 0050380 | molecular_function | undecaprenyl-diphosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue 46E A 301 |
| Chain | Residue |
| A | GLN50 |
| A | VAL88 |
| A | GLY89 |
| A | LYS93 |
| A | PRO160 |
| A | PHE166 |
| A | SER169 |
| A | TRP170 |
| A | LEU222 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 111 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:24821770 |
| Chain | Residue | Details |
| A | ARG2-ILE24 | |
| A | ILE55-TRP66 | |
| A | ILE72-SER94 | |
| A | GLY162-GLY176 | |
| A | ARG183-LEU202 | |
| A | PRO209-ARG232 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 100 |
| Details | TOPO_DOM: Periplasmic => ECO:0000305|PubMed:24821770 |
| Chain | Residue | Details |
| A | SER25-VAL54 | |
| A | TRP95-SER161 | |
| A | LEU203-TRP208 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:24821770 |
| Chain | Residue | Details |
| A | CYS67-ARG71 | |
| A | LEU177-ARG182 | |
| A | ILE233-SER254 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor; for a subset of substrates => ECO:0000269|PubMed:27405756 |
| Chain | Residue | Details |
| A | HIS163 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:27405756 |
| Chain | Residue | Details |
| A | HIS207 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Stabilizes the active site histidine for nucleophilic attack => ECO:0000305|PubMed:27405756 |
| Chain | Residue | Details |
| A | ASP211 |
