5JWM
Bivalent BET Bromodomain Inhibition
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue 6ON A 501 |
| Chain | Residue |
| A | TRP374 |
| A | VAL439 |
| A | MET442 |
| A | HOH602 |
| A | HOH616 |
| A | HOH628 |
| B | TRP374 |
| B | PRO375 |
| B | PHE376 |
| B | LEU385 |
| B | GLY386 |
| A | PRO375 |
| B | LEU387 |
| B | ASN433 |
| B | HIS437 |
| B | GLU438 |
| B | VAL439 |
| B | HOH501 |
| B | HOH513 |
| B | HOH537 |
| A | PHE376 |
| A | LEU385 |
| A | LEU387 |
| A | ASP389 |
| A | ASN433 |
| A | HIS437 |
| A | GLU438 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Acetylated histone binding => ECO:0000269|PubMed:22464331 |
| Chain | Residue | Details |
| A | ASN433 | |
| B | ASN433 |
