5JTA
Neutral trehalase Nth1 from Saccharomyces cerevisiae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004555 | molecular_function | alpha,alpha-trehalase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0005991 | biological_process | trehalose metabolic process |
| A | 0005993 | biological_process | trehalose catabolic process |
| A | 0015927 | molecular_function | trehalase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071465 | biological_process | cellular response to desiccation |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:29087344, ECO:0007744|PDB:5M4A |
| Chain | Residue | Details |
| A | ASP478 | |
| A | GLU674 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29087344, ECO:0007744|PDB:5N6N |
| Chain | Residue | Details |
| A | ASP114 | |
| A | ASP116 | |
| A | ASN118 | |
| A | GLN120 | |
| A | ASP125 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P13482 |
| Chain | Residue | Details |
| A | ARG302 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29087344, ECO:0007744|PDB:5M4A, ECO:0007744|PDB:5N6N |
| Chain | Residue | Details |
| A | TRP309 | |
| A | ASN346 | |
| A | ARG355 | |
| A | GLU424 | |
| A | ARG473 | |
| A | GLY476 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: BMH1 binding => ECO:0000269|PubMed:29087344, ECO:0007744|PDB:5N6N |
| Chain | Residue | Details |
| A | ARG55 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | SER2 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:22320399, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | SER20 | |
| A | SER21 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | SER23 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | THR58 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:22320399, ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | SER60 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | SER66 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:22320399, ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | SER83 |
