5JP9
Crystal Structure of cytidine monophosphate hydroxymethylase MilA with dCMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004799 | molecular_function | thymidylate synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006231 | biological_process | dTMP biosynthetic process |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016741 | molecular_function | transferase activity, transferring one-carbon groups |
| A | 0032259 | biological_process | methylation |
| B | 0004799 | molecular_function | thymidylate synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006231 | biological_process | dTMP biosynthetic process |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0016741 | molecular_function | transferase activity, transferring one-carbon groups |
| B | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue DCM A 401 |
| Chain | Residue |
| A | ARG31 |
| A | TYR218 |
| A | HOH526 |
| A | HOH536 |
| A | HOH537 |
| B | LYS133 |
| B | ARG134 |
| B | HOH633 |
| A | TYR104 |
| A | CYS155 |
| A | ARG175 |
| A | ALA176 |
| A | ASN177 |
| A | ASP178 |
| A | ASP186 |
| A | HIS216 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue DCM B 401 |
| Chain | Residue |
| A | LYS133 |
| A | ARG134 |
| A | HOH602 |
| B | ARG31 |
| B | TYR104 |
| B | CYS155 |
| B | ARG175 |
| B | ALA176 |
| B | ASN177 |
| B | ASP178 |
| B | ASP186 |
| B | HIS216 |
| B | TYR218 |
| B | HOH530 |
| B | HOH542 |
| B | HOH552 |
