5JP5

Crystal structure of rat Galectin 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0010628	biological_process	positive regulation of gene expression
A	0016936	molecular_function	galactoside binding
A	0030246	molecular_function	carbohydrate binding
A	0030395	molecular_function	lactose binding
A	0032689	biological_process	negative regulation of type II interferon production
A	0070234	biological_process	positive regulation of T cell apoptotic process
A	2000562	biological_process	negative regulation of CD4-positive, alpha-beta T cell proliferation
B	0005634	cellular_component	nucleus
B	0005829	cellular_component	cytosol
B	0010628	biological_process	positive regulation of gene expression
B	0016936	molecular_function	galactoside binding
B	0030246	molecular_function	carbohydrate binding
B	0030395	molecular_function	lactose binding
B	0032689	biological_process	negative regulation of type II interferon production
B	0070234	biological_process	positive regulation of T cell apoptotic process
B	2000562	biological_process	negative regulation of CD4-positive, alpha-beta T cell proliferation
C	0005634	cellular_component	nucleus
C	0005829	cellular_component	cytosol
C	0010628	biological_process	positive regulation of gene expression
C	0016936	molecular_function	galactoside binding
C	0030246	molecular_function	carbohydrate binding
C	0030395	molecular_function	lactose binding
C	0032689	biological_process	negative regulation of type II interferon production
C	0070234	biological_process	positive regulation of T cell apoptotic process
C	2000562	biological_process	negative regulation of CD4-positive, alpha-beta T cell proliferation
D	0005634	cellular_component	nucleus
D	0005829	cellular_component	cytosol
D	0010628	biological_process	positive regulation of gene expression
D	0016936	molecular_function	galactoside binding
D	0030246	molecular_function	carbohydrate binding
D	0030395	molecular_function	lactose binding
D	0032689	biological_process	negative regulation of type II interferon production
D	0070234	biological_process	positive regulation of T cell apoptotic process
D	2000562	biological_process	negative regulation of CD4-positive, alpha-beta T cell proliferation
E	0005634	cellular_component	nucleus
E	0005829	cellular_component	cytosol
E	0010628	biological_process	positive regulation of gene expression
E	0016936	molecular_function	galactoside binding
E	0030246	molecular_function	carbohydrate binding
E	0030395	molecular_function	lactose binding
E	0032689	biological_process	negative regulation of type II interferon production
E	0070234	biological_process	positive regulation of T cell apoptotic process
E	2000562	biological_process	negative regulation of CD4-positive, alpha-beta T cell proliferation
F	0005634	cellular_component	nucleus
F	0005829	cellular_component	cytosol
F	0010628	biological_process	positive regulation of gene expression
F	0016936	molecular_function	galactoside binding
F	0030246	molecular_function	carbohydrate binding
F	0030395	molecular_function	lactose binding
F	0032689	biological_process	negative regulation of type II interferon production
F	0070234	biological_process	positive regulation of T cell apoptotic process
F	2000562	biological_process	negative regulation of CD4-positive, alpha-beta T cell proliferation

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue PEG A 201

Chain	Residue
A	HIS57
A	ARG61
A	ASN70
A	TRP77
A	GLU80
A	HOH305

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site_id	AC2
Number of Residues	6
Details	binding site for residue PEG C 201

Chain	Residue
C	HOH302
C	HOH303
C	HOH394
B	GLY93
C	SER76
C	TRP77

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site_id	AC3
Number of Residues	4
Details	binding site for residue PEG D 201

Chain	Residue
D	SER30
D	GLU144
D	HOH301
D	HOH357

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site_id	AC4
Number of Residues	2
Details	binding site for residue PEG F 201

Chain	Residue
A	HIS121
F	SER30

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	TRP77
B	TRP77
C	TRP77
D	TRP77
E	TRP77
F	TRP77

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site_id	SWS_FT_FI2
Number of Residues	6
Details	MOD_RES: N-acetylserine => ECO:0000269|PubMed:7890611

Chain	Residue	Details
A	SER2
B	SER2
C	SER2
D	SER2
E	SER2
F	SER2

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