5JKI

Crystal structure of the first transmembrane PAP2 type phosphatidylglycerolphosphate phosphatase from Bacillus subtilis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0008962	molecular_function	phosphatidylglycerophosphatase activity
A	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue WO4 A 300

Chain	Residue
A	LYS96
A	ARG103
A	GLU112
A	SER119
A	GLY120
A	HIS121
A	ARG165
A	HIS171

---

site_id	AC2
Number of Residues	2
Details	binding site for residue OLC A 301

Chain	Residue
A	ARG89
A	GLY86

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	115
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	60
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Region: {"description":"Phosphatase sequence motif I","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Region: {"description":"Phosphatase sequence motif II","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	11
Details	Region: {"description":"Phosphatase sequence motif III","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Active site: {"description":"Proton donors","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Site: {"description":"Stabilizes the active site histidine for nucleophilic attack","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---