5JKI
Crystal structure of the first transmembrane PAP2 type phosphatidylglycerolphosphate phosphatase from Bacillus subtilis
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue WO4 A 300 |
| Chain | Residue |
| A | LYS96 |
| A | ARG103 |
| A | GLU112 |
| A | SER119 |
| A | GLY120 |
| A | HIS121 |
| A | ARG165 |
| A | HIS171 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue OLC A 301 |
| Chain | Residue |
| A | ARG89 |
| A | GLY86 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 112 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30272004","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5JKI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6FMX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 60 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Region: {"description":"Phosphatase sequence motif I","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Region: {"description":"Phosphatase sequence motif II","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 11 |
| Details | Region: {"description":"Phosphatase sequence motif III","evidences":[{"source":"PubMed","id":"28168443","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P0A924","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"P0A924","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Site: {"description":"Stabilizes the active site histidine for nucleophilic attack","evidences":[{"source":"UniProtKB","id":"P0A924","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
