5JK9

Crystal structure of human IZUMO1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005102	molecular_function	signaling receptor binding
A	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
A	0016020	cellular_component	membrane
A	0035036	biological_process	sperm-egg recognition
B	0005102	molecular_function	signaling receptor binding
B	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
B	0016020	cellular_component	membrane
B	0035036	biological_process	sperm-egg recognition
C	0005102	molecular_function	signaling receptor binding
C	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
C	0016020	cellular_component	membrane
C	0035036	biological_process	sperm-egg recognition
D	0005102	molecular_function	signaling receptor binding
D	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
D	0016020	cellular_component	membrane
D	0035036	biological_process	sperm-egg recognition
E	0005102	molecular_function	signaling receptor binding
E	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
E	0016020	cellular_component	membrane
E	0035036	biological_process	sperm-egg recognition
F	0005102	molecular_function	signaling receptor binding
F	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
F	0016020	cellular_component	membrane
F	0035036	biological_process	sperm-egg recognition

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	420
Details	Domain: {"description":"Ig-like C2-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	72
Details	Region: {"description":"Important for interaction with IZUMO1R","evidences":[{"source":"PubMed","id":"27309818","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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