5JK0

Crystal structure of XerH site-specific recombinase bound to difH substrate: pre-cleavage complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005737	cellular_component	cytoplasm
A	0006310	biological_process	DNA recombination
A	0007059	biological_process	chromosome segregation
A	0009037	molecular_function	tyrosine-based site-specific recombinase activity
A	0015074	biological_process	DNA integration
A	0051301	biological_process	cell division
B	0003677	molecular_function	DNA binding
B	0005737	cellular_component	cytoplasm
B	0006310	biological_process	DNA recombination
B	0007059	biological_process	chromosome segregation
B	0009037	molecular_function	tyrosine-based site-specific recombinase activity
B	0015074	biological_process	DNA integration
B	0051301	biological_process	cell division
C	0003677	molecular_function	DNA binding
C	0005737	cellular_component	cytoplasm
C	0006310	biological_process	DNA recombination
C	0007059	biological_process	chromosome segregation
C	0009037	molecular_function	tyrosine-based site-specific recombinase activity
C	0015074	biological_process	DNA integration
C	0051301	biological_process	cell division
D	0003677	molecular_function	DNA binding
D	0005737	cellular_component	cytoplasm
D	0006310	biological_process	DNA recombination
D	0007059	biological_process	chromosome segregation
D	0009037	molecular_function	tyrosine-based site-specific recombinase activity
D	0015074	biological_process	DNA integration
D	0051301	biological_process	cell division

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue GOL A 401

Chain	Residue
A	GLN56
A	HOH580
A	HOH601
C	LEU184
C	PHE209

---

site_id	AC2
Number of Residues	2
Details	binding site for residue GOL A 402

Chain	Residue
A	TYR232
A	LEU261

---

site_id	AC3
Number of Residues	4
Details	binding site for residue EDO A 403

Chain	Residue
A	LYS88
A	PHE98
A	TYR85
A	PHE86

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CL A 404

Chain	Residue
A	LEU326
C	LEU326

---

site_id	AC5
Number of Residues	3
Details	binding site for residue GOL B 401

Chain	Residue
B	ASP140
B	HOH598
D	LYS141

---

site_id	AC6
Number of Residues	6
Details	binding site for residue GOL B 402

Chain	Residue
B	THR28
B	LEU30
B	SER31
B	ASN32
B	HOH535
C	SER114

---

site_id	AC7
Number of Residues	3
Details	binding site for residue GOL B 403

Chain	Residue
B	TYR267
B	GLN278
B	HOH584

---

site_id	AC8
Number of Residues	4
Details	binding site for residue EDO B 404

Chain	Residue
B	GLN38
B	ASN39
C	LYS88
C	TYR116

---

site_id	AC9
Number of Residues	4
Details	binding site for residue PEG B 405

Chain	Residue
B	ARG21
B	ARG24
B	LEU48
B	ASN49

---

site_id	AD1
Number of Residues	6
Details	binding site for residue EDO C 401

Chain	Residue
A	ASN154
A	HOH532
C	TYR25
C	TYR138
C	GLN142
C	HOH557

---

site_id	AD2
Number of Residues	7
Details	binding site for residue EDO C 402

Chain	Residue
C	ASN73
C	THR74
C	LEU77
C	PRO78
C	HOH534
F	DA9
F	HOH107

---

site_id	AD3
Number of Residues	2
Details	binding site for residue EDO D 401

Chain	Residue
D	LYS81
D	GLU84

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01246

Chain	Residue	Details
A	ARG213
A	LYS239
A	HIS309
A	ARG312
A	HIS335
B	ARG213
B	LYS239
B	HIS309
B	ARG312
B	HIS335
C	ARG213
C	LYS239
C	HIS309
C	ARG312
C	HIS335
D	ARG213
D	LYS239
D	HIS309
D	ARG312
D	HIS335

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: O-(3'-phospho-DNA)-tyrosine intermediate => ECO:0000255|PROSITE-ProRule:PRU01246

Chain	Residue	Details
A	TYR344
B	TYR344
C	TYR344
D	TYR344

---