5JK0
Crystal structure of XerH site-specific recombinase bound to difH substrate: pre-cleavage complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006310 | biological_process | DNA recombination |
| A | 0007059 | biological_process | chromosome segregation |
| A | 0009009 | molecular_function | site-specific recombinase activity |
| A | 0009037 | molecular_function | tyrosine-based site-specific recombinase activity |
| A | 0015074 | biological_process | DNA integration |
| A | 0051301 | biological_process | cell division |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006310 | biological_process | DNA recombination |
| B | 0007059 | biological_process | chromosome segregation |
| B | 0009009 | molecular_function | site-specific recombinase activity |
| B | 0009037 | molecular_function | tyrosine-based site-specific recombinase activity |
| B | 0015074 | biological_process | DNA integration |
| B | 0051301 | biological_process | cell division |
| C | 0003677 | molecular_function | DNA binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006310 | biological_process | DNA recombination |
| C | 0007059 | biological_process | chromosome segregation |
| C | 0009009 | molecular_function | site-specific recombinase activity |
| C | 0009037 | molecular_function | tyrosine-based site-specific recombinase activity |
| C | 0015074 | biological_process | DNA integration |
| C | 0051301 | biological_process | cell division |
| D | 0003677 | molecular_function | DNA binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006310 | biological_process | DNA recombination |
| D | 0007059 | biological_process | chromosome segregation |
| D | 0009009 | molecular_function | site-specific recombinase activity |
| D | 0009037 | molecular_function | tyrosine-based site-specific recombinase activity |
| D | 0015074 | biological_process | DNA integration |
| D | 0051301 | biological_process | cell division |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | GLN56 |
| A | HOH580 |
| A | HOH601 |
| C | LEU184 |
| C | PHE209 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | TYR232 |
| A | LEU261 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | LYS88 |
| A | PHE98 |
| A | TYR85 |
| A | PHE86 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | LEU326 |
| C | LEU326 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | ASP140 |
| B | HOH598 |
| D | LYS141 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | THR28 |
| B | LEU30 |
| B | SER31 |
| B | ASN32 |
| B | HOH535 |
| C | SER114 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | TYR267 |
| B | GLN278 |
| B | HOH584 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | GLN38 |
| B | ASN39 |
| C | LYS88 |
| C | TYR116 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 405 |
| Chain | Residue |
| B | ARG21 |
| B | ARG24 |
| B | LEU48 |
| B | ASN49 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 401 |
| Chain | Residue |
| A | ASN154 |
| A | HOH532 |
| C | TYR25 |
| C | TYR138 |
| C | GLN142 |
| C | HOH557 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 402 |
| Chain | Residue |
| C | ASN73 |
| C | THR74 |
| C | LEU77 |
| C | PRO78 |
| C | HOH534 |
| F | DA9 |
| F | HOH107 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 401 |
| Chain | Residue |
| D | LYS81 |
| D | GLU84 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 374 |
| Details | Domain: {"description":"Tyr recombinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01246","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01246","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"O-(3'-phospho-DNA)-tyrosine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU01246","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 194 |
| Details | Domain: {"description":"Core-binding (CB)","evidences":[{"source":"PROSITE-ProRule","id":"PRU01248","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
