5JJI
Rho transcription termination factor bound to rU7 and 6 ADP-BeF3 molecules
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006353 | biological_process | DNA-templated transcription termination |
| A | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0006353 | biological_process | DNA-templated transcription termination |
| B | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042802 | molecular_function | identical protein binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0003723 | molecular_function | RNA binding |
| C | 0004386 | molecular_function | helicase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0006351 | biological_process | DNA-templated transcription |
| C | 0006353 | biological_process | DNA-templated transcription termination |
| C | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| C | 0016020 | cellular_component | membrane |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0042802 | molecular_function | identical protein binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003723 | molecular_function | RNA binding |
| D | 0004386 | molecular_function | helicase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0006351 | biological_process | DNA-templated transcription |
| D | 0006353 | biological_process | DNA-templated transcription termination |
| D | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| D | 0016020 | cellular_component | membrane |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0042802 | molecular_function | identical protein binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0003676 | molecular_function | nucleic acid binding |
| E | 0003723 | molecular_function | RNA binding |
| E | 0004386 | molecular_function | helicase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005829 | cellular_component | cytosol |
| E | 0006351 | biological_process | DNA-templated transcription |
| E | 0006353 | biological_process | DNA-templated transcription termination |
| E | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| E | 0016020 | cellular_component | membrane |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0042802 | molecular_function | identical protein binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0003676 | molecular_function | nucleic acid binding |
| F | 0003723 | molecular_function | RNA binding |
| F | 0004386 | molecular_function | helicase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005829 | cellular_component | cytosol |
| F | 0006351 | biological_process | DNA-templated transcription |
| F | 0006353 | biological_process | DNA-templated transcription termination |
| F | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| F | 0016020 | cellular_component | membrane |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ADP A 1000 |
| Chain | Residue |
| A | THR158 |
| A | MG1001 |
| A | BEF1002 |
| A | HOH1103 |
| A | HOH1112 |
| A | HOH1124 |
| B | ARG366 |
| B | LYS367 |
| A | PRO179 |
| A | LYS181 |
| A | ALA182 |
| A | GLY183 |
| A | LYS184 |
| A | THR185 |
| A | MSE186 |
| A | PHE355 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1001 |
| Chain | Residue |
| A | THR185 |
| A | ADP1000 |
| A | BEF1002 |
| A | HOH1103 |
| A | HOH1106 |
| A | HOH1112 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue BEF A 1002 |
| Chain | Residue |
| A | PRO180 |
| A | LYS184 |
| A | ARG212 |
| A | LEU320 |
| A | ADP1000 |
| A | MG1001 |
| A | HOH1103 |
| A | HOH1106 |
| A | HOH1112 |
| B | GLY337 |
| B | ARG366 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue ADP B 501 |
| Chain | Residue |
| B | PRO179 |
| B | LYS181 |
| B | ALA182 |
| B | GLY183 |
| B | LYS184 |
| B | THR185 |
| B | MSE186 |
| B | PHE355 |
| B | MG502 |
| B | BEF503 |
| B | HOH602 |
| B | HOH642 |
| B | HOH648 |
| C | ARG366 |
| C | LYS367 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 502 |
| Chain | Residue |
| B | THR185 |
| B | ADP501 |
| B | BEF503 |
| B | HOH602 |
| B | HOH615 |
| B | HOH642 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue BEF B 503 |
| Chain | Residue |
| B | PRO180 |
| B | LYS181 |
| B | LYS184 |
| B | ARG212 |
| B | LEU320 |
| B | ADP501 |
| B | MG502 |
| B | HOH602 |
| B | HOH615 |
| B | HOH635 |
| B | HOH642 |
| C | GLY337 |
| C | ARG366 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MPD B 504 |
| Chain | Residue |
| B | ARG170 |
| B | ASP259 |
| B | ASN306 |
| B | VAL307 |
| B | GLY311 |
| B | HOH639 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | binding site for residue ADP C 1000 |
| Chain | Residue |
| C | PRO179 |
| C | LYS181 |
| C | ALA182 |
| C | GLY183 |
| C | LYS184 |
| C | THR185 |
| C | MSE186 |
| C | PHE355 |
| C | MG1001 |
| C | BEF1002 |
| C | HOH1105 |
| C | HOH1145 |
| C | HOH1160 |
| D | ARG366 |
| D | LYS367 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 1001 |
| Chain | Residue |
| C | THR185 |
| C | ADP1000 |
| C | BEF1002 |
| C | HOH1104 |
| C | HOH1105 |
| C | HOH1145 |
| site_id | AD1 |
| Number of Residues | 13 |
| Details | binding site for residue BEF C 1002 |
| Chain | Residue |
| C | ADP1000 |
| C | MG1001 |
| C | HOH1104 |
| C | HOH1105 |
| C | HOH1145 |
| C | HOH1155 |
| D | GLY337 |
| D | ARG366 |
| C | PRO180 |
| C | LYS181 |
| C | LYS184 |
| C | ARG212 |
| C | LEU320 |
| site_id | AD2 |
| Number of Residues | 14 |
| Details | binding site for residue ADP D 1000 |
| Chain | Residue |
| D | PRO179 |
| D | LYS181 |
| D | ALA182 |
| D | GLY183 |
| D | LYS184 |
| D | THR185 |
| D | MSE186 |
| D | PHE355 |
| D | MG1001 |
| D | BEF1002 |
| D | HOH1111 |
| D | HOH1126 |
| E | ARG366 |
| E | LYS367 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 1001 |
| Chain | Residue |
| D | THR185 |
| D | ADP1000 |
| D | BEF1002 |
| D | HOH1111 |
| D | HOH1126 |
| D | HOH1133 |
| site_id | AD4 |
| Number of Residues | 12 |
| Details | binding site for residue BEF D 1002 |
| Chain | Residue |
| D | PRO180 |
| D | LYS181 |
| D | LYS184 |
| D | ARG212 |
| D | ADP1000 |
| D | MG1001 |
| D | HOH1111 |
| D | HOH1121 |
| D | HOH1126 |
| D | HOH1133 |
| E | GLY337 |
| E | ARG366 |
| site_id | AD5 |
| Number of Residues | 14 |
| Details | binding site for residue ADP E 1000 |
| Chain | Residue |
| E | THR158 |
| E | PRO180 |
| E | LYS181 |
| E | ALA182 |
| E | GLY183 |
| E | LYS184 |
| E | THR185 |
| E | MSE186 |
| E | PHE355 |
| E | MG1001 |
| E | BEF1002 |
| E | HOH1104 |
| E | HOH1110 |
| E | HOH1112 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue MG E 1001 |
| Chain | Residue |
| E | THR185 |
| E | ADP1000 |
| E | BEF1002 |
| E | HOH1104 |
| E | HOH1110 |
| E | HOH1115 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue BEF E 1002 |
| Chain | Residue |
| E | PRO180 |
| E | LYS184 |
| E | ARG212 |
| E | ADP1000 |
| E | MG1001 |
| E | HOH1110 |
| E | HOH1115 |
| F | ARG366 |
| site_id | AD8 |
| Number of Residues | 15 |
| Details | binding site for residue ADP F 1000 |
| Chain | Residue |
| A | ARG366 |
| A | LYS367 |
| A | GLU369 |
| F | PRO180 |
| F | LYS181 |
| F | ALA182 |
| F | GLY183 |
| F | LYS184 |
| F | THR185 |
| F | MSE186 |
| F | PHE355 |
| F | MG1001 |
| F | BEF1002 |
| F | HOH1101 |
| F | HOH1105 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue MG F 1001 |
| Chain | Residue |
| F | THR185 |
| F | ADP1000 |
| F | BEF1002 |
| F | HOH1101 |
| F | HOH1103 |
| F | HOH1105 |
| site_id | AE1 |
| Number of Residues | 11 |
| Details | binding site for residue BEF F 1002 |
| Chain | Residue |
| A | ARG366 |
| F | PRO180 |
| F | LYS184 |
| F | ARG212 |
| F | LEU320 |
| F | ADP1000 |
| F | MG1001 |
| F | HOH1101 |
| F | HOH1103 |
| F | HOH1105 |
| F | HOH1108 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 52 |
| Details | Region: {"description":"RNA-binding 1","evidences":[{"source":"HAMAP-Rule","id":"MF_01884","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Region: {"description":"RNA-binding 2","evidences":[{"source":"HAMAP-Rule","id":"MF_01884","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 66 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01884","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Site: {"description":"RNA-binding 2","evidences":[{"source":"HAMAP-Rule","id":"MF_01884","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 150 |
| Details | Domain: {"description":"Rho RNA-BD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01203","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
