Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004096 | molecular_function | catalase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005829 | cellular_component | cytosol |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070301 | biological_process | cellular response to hydrogen peroxide |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue HEM A 1500 |
| Chain | Residue |
| A | GLY133 |
| A | THR319 |
| A | HIS320 |
| A | THR358 |
| A | SER359 |
| A | TRP365 |
| A | SER423 |
| A | HOH1636 |
| A | HOH1685 |
| A | HOH1710 |
| A | LEU134 |
| A | TRP140 |
| A | LEU309 |
| A | GLY313 |
| A | HIS314 |
| A | PHE316 |
| A | GLY317 |
| A | LYS318 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue HEM B 1500 |
| Chain | Residue |
| B | GLY133 |
| B | LEU134 |
| B | TRP140 |
| B | VAL274 |
| B | LEU309 |
| B | ILE310 |
| B | GLY313 |
| B | HIS314 |
| B | GLY317 |
| B | LYS318 |
| B | THR319 |
| B | HIS320 |
| B | THR358 |
| B | SER359 |
| B | TRP365 |
| B | SER423 |
| B | HOH1650 |
| B | HOH1754 |
| B | HOH1858 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide TYR B 273 and MET B 299 |
| Chain | Residue |
| B | TRP140 |
| B | GLY144 |
| B | TYR146 |
| B | ALA265 |
| B | ALA266 |
| B | THR267 |
| B | LEU271 |
| B | ILE272 |
| B | VAL274 |
| B | ALA295 |
| B | PHE296 |
| B | GLY297 |
| B | ARG298 |
| B | GLY300 |
| B | MET301 |
| B | ARG461 |
| B | HOH1660 |
| B | HOH1737 |
| B | HOH1804 |
Functional Information from PROSITE/UniProt
| site_id | PS00435 |
| Number of Residues | 11 |
| Details | PEROXIDASE_1 Peroxidases proximal heme-ligand signature. TVALIAGGHAF |
| Chain | Residue | Details |
| A | THR306-PHE316 | |
| site_id | PS00436 |
| Number of Residues | 12 |
| Details | PEROXIDASE_2 Peroxidases active site signature. GGlfVRMaWHSA |
| Chain | Residue | Details |
| A | GLY132-ALA143 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_03108","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-299)"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-140)"} |
