5JER
Structure of Rotavirus NSP1 bound to IRF-3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0003700 | molecular_function | DNA-binding transcription factor activity |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:23746807 |
| Chain | Residue | Details |
| A | THR237 | |
| E | THR244 | |
| E | THR253 | |
| E | THR404 | |
| G | THR237 | |
| G | THR244 | |
| G | THR253 | |
| G | THR404 | |
| A | THR244 | |
| A | THR253 | |
| A | THR404 | |
| C | THR237 | |
| C | THR244 | |
| C | THR253 | |
| C | THR404 | |
| E | THR237 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P70671 |
| Chain | Residue | Details |
| A | LYS366 | |
| C | LYS366 | |
| E | LYS366 | |
| G | LYS366 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:22394562 |
| Chain | Residue | Details |
| A | SER385 | |
| C | SER385 | |
| E | SER385 | |
| G | SER385 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by TBK1 => ECO:0000269|PubMed:22394562, ECO:0000269|PubMed:23746807, ECO:0000269|PubMed:27302953, ECO:0000269|PubMed:36603579 |
| Chain | Residue | Details |
| A | SER386 | |
| C | SER386 | |
| E | SER386 | |
| G | SER386 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by IKKE and TBK1 => ECO:0000269|PubMed:22394562, ECO:0000269|PubMed:23478265, ECO:0000269|PubMed:27302953, ECO:0000269|PubMed:36603579 |
| Chain | Residue | Details |
| A | SER396 | |
| C | SER396 | |
| E | SER396 | |
| G | SER396 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:23746807 |
| Chain | Residue | Details |
| A | SER398 | |
| A | SER427 | |
| C | SER398 | |
| C | SER427 | |
| E | SER398 | |
| E | SER427 | |
| G | SER398 | |
| G | SER427 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 16 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15) => ECO:0000269|PubMed:20308324 |
| Chain | Residue | Details |
| A | LYS193 | |
| E | LYS360 | |
| E | LYS366 | |
| G | LYS193 | |
| G | LYS360 | |
| G | LYS366 | |
| A | LYS360 | |
| A | LYS366 | |
| C | LYS193 | |
| C | LYS360 | |
| C | LYS366 | |
| E | LYS193 |
