5JD0
crystal structure of ARAP3 RhoGAP domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005096 | molecular_function | GTPase activator activity |
| A | 0005547 | molecular_function | phosphatidylinositol-3,4,5-trisphosphate binding |
| A | 0007165 | biological_process | signal transduction |
| A | 0043547 | biological_process | positive regulation of GTPase activity |
| B | 0005096 | molecular_function | GTPase activator activity |
| B | 0005547 | molecular_function | phosphatidylinositol-3,4,5-trisphosphate binding |
| B | 0007165 | biological_process | signal transduction |
| B | 0043547 | biological_process | positive regulation of GTPase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 362 |
| Details | Domain: {"description":"Rho-GAP","evidences":[{"source":"PROSITE-ProRule","id":"PRU00172","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Arginine finger; crucial for GTP hydrolysis by stabilizing the transition state","evidences":[{"source":"PROSITE-ProRule","id":"PRU00172","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
