5JCZ

Rab11 bound to MyoVa-GTD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
I	0003924	molecular_function	GTPase activity
I	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 201

Chain	Residue
A	SER25
A	THR43
A	GDP202
A	BEF203
A	HOH316
A	HOH326

---

site_id	AC2
Number of Residues	23
Details	binding site for residue GDP A 202

Chain	Residue
A	LYS24
A	SER25
A	ASN26
A	PHE36
A	ASN37
A	LEU38
A	SER40
A	ASN124
A	LYS125
A	ASP127
A	LEU128
A	SER154
A	ALA155
A	LEU156
A	MG201
A	BEF203
A	HOH308
A	HOH316
A	HOH326
A	HOH336
A	GLY21
A	VAL22
A	GLY23

---

site_id	AC3
Number of Residues	11
Details	binding site for residue BEF A 203

Chain	Residue
A	SER20
A	LYS24
A	SER42
A	THR43
A	ALA68
A	GLY69
A	MG201
A	GDP202
A	HOH316
A	HOH326
A	HOH431

---

site_id	AC4
Number of Residues	6
Details	binding site for residue EDO A 204

Chain	Residue
A	ILE17
A	GLY18
A	THR67
A	ARG72
A	TRP105
A	GLU108

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO A 205

Chain	Residue
A	ARG129
A	ARG132
A	HOH399
C	CYS1674

---

site_id	AC6
Number of Residues	6
Details	binding site for residue EDO A 206

Chain	Residue
A	TYR99
A	GLU100
A	VAL102
A	GLU103
A	PHE142
A	HOH357

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ACT A 207

Chain	Residue
A	ARG140
A	ILE151
A	GLU152
A	ASN160

---

site_id	AC8
Number of Residues	2
Details	binding site for residue GOL A 208

Chain	Residue
A	TYR10
A	LEU11

---

site_id	AC9
Number of Residues	8
Details	binding site for residue EDO B 1901

Chain	Residue
B	TYR1692
B	GLY1695
B	ALA1696
B	THR1741
B	LEU1742
B	PRO1744
B	LEU1745
B	MET1817

---

site_id	AD1
Number of Residues	5
Details	binding site for residue EDO B 1902

Chain	Residue
A	HOH412
B	GLU1725
B	GLU1726
B	ARG1729
B	HOH2046

---

site_id	AD2
Number of Residues	5
Details	binding site for residue GOL B 1903

Chain	Residue
A	GLU47
B	ARG1718
B	GLU1725
B	LYS1739
B	GLU1743

---

site_id	AD3
Number of Residues	9
Details	binding site for residue EDO C 1901

Chain	Residue
C	TYR1692
C	GLY1695
C	ALA1696
C	THR1741
C	LEU1742
C	PRO1744
C	LEU1745
C	MET1817
C	HOH2080

---

site_id	AD4
Number of Residues	6
Details	binding site for residue EDO C 1902

Chain	Residue
C	LEU1752
C	GLN1753
C	VAL1754
C	LYS1756
C	TYR1784
D	TYR73

---

site_id	AD5
Number of Residues	3
Details	binding site for residue EDO C 1903

Chain	Residue
C	LEU1491
C	LYS1540
C	LYS1544

---

site_id	AD6
Number of Residues	5
Details	binding site for residue EDO C 1904

Chain	Residue
C	THR1826
C	PRO1828
C	HOH2168
C	HOH2241
C	GLU1681

---

site_id	AD7
Number of Residues	5
Details	binding site for residue MG C 1905

Chain	Residue
C	ARG1807
C	ARG1809
E	ASN1590
E	HOH2091
E	HOH2096

---

site_id	AD8
Number of Residues	1
Details	binding site for residue ACT C 1906

Chain	Residue
C	GLN1840

---

site_id	AD9
Number of Residues	6
Details	binding site for residue MG D 201

Chain	Residue
D	SER25
D	THR43
D	GDP202
D	BEF203
D	HOH309
D	HOH326

---

site_id	AE1
Number of Residues	23
Details	binding site for residue GDP D 202

Chain	Residue
D	GLY21
D	VAL22
D	GLY23
D	LYS24
D	SER25
D	ASN26
D	PHE36
D	ASN37
D	LEU38
D	SER40
D	ASN124
D	LYS125
D	ASP127
D	LEU128
D	SER154
D	ALA155
D	LEU156
D	MG201
D	BEF203
D	HOH309
D	HOH322
D	HOH326
D	HOH333

---

site_id	AE2
Number of Residues	10
Details	binding site for residue BEF D 203

Chain	Residue
D	SER20
D	LYS24
D	SER42
D	THR43
D	ALA68
D	GLY69
D	MG201
D	GDP202
D	HOH309
D	HOH326

---

site_id	AE3
Number of Residues	6
Details	binding site for residue EDO D 204

Chain	Residue
D	TYR99
D	GLU100
D	VAL102
D	GLU103
D	PHE142
D	HOH343

---

site_id	AE4
Number of Residues	6
Details	binding site for residue EDO D 205

Chain	Residue
D	ILE17
D	GLY18
D	THR67
D	ARG72
D	TRP105
D	GLU108

---

site_id	AE5
Number of Residues	9
Details	binding site for residue EDO E 1901

Chain	Residue
E	TYR1692
E	GLY1695
E	ALA1696
E	THR1741
E	LEU1742
E	PRO1744
E	LEU1745
E	MET1817
E	HOH2014

---

site_id	AE6
Number of Residues	2
Details	binding site for residue EDO E 1902

Chain	Residue
E	LYS1779
E	ASN1782

---

site_id	AE7
Number of Residues	6
Details	binding site for residue MG I 201

Chain	Residue
I	SER25
I	THR43
I	GDP202
I	BEF203
I	HOH301
I	HOH303

---

site_id	AE8
Number of Residues	22
Details	binding site for residue GDP I 202

Chain	Residue
I	GLY21
I	VAL22
I	GLY23
I	LYS24
I	SER25
I	ASN26
I	ASN34
I	PHE36
I	ASN37
I	LEU38
I	SER40
I	ASN124
I	LYS125
I	ASP127
I	SER154
I	ALA155
I	LEU156
I	MG201
I	BEF203
I	HOH301
I	HOH303
I	HOH307

---

site_id	AE9
Number of Residues	9
Details	binding site for residue BEF I 203

Chain	Residue
I	SER20
I	LYS24
I	SER42
I	THR43
I	ALA68
I	GLY69
I	MG201
I	GDP202
I	HOH303

---

site_id	AF1
Number of Residues	9
Details	binding site for Ligand ASP I 127 bound to ASN I 34

Chain	Residue
I	ARG33
I	ASN34
I	GLU35
I	LYS125
I	SER126
I	ARG129
I	SER154
I	ASP157
I	GDP202

---

site_id	AF2
Number of Residues	9
Details	binding site for Ligand ASP I 127 bound to ASN I 34

Chain	Residue
I	ARG33
I	ASN34
I	GLU35
I	LYS125
I	SER126
I	ARG129
I	SER154
I	ASP157
I	GDP202

---

site_id	AF3
Number of Residues	15
Details	binding site for Ligand SER I 154 bound to ASN I 34

Chain	Residue
I	ARG30
I	ASN34
I	GLU35
I	ASN124
I	SER126
I	ASP127
I	THR153
I	ALA155
I	LEU156
I	ASP157
I	SER158
I	SER158
I	THR159
I	VAL161
I	GDP202

---

site_id	AF4
Number of Residues	15
Details	binding site for Ligand SER I 154 bound to ASN I 34

Chain	Residue
I	ARG30
I	ASN34
I	GLU35
I	ASN124
I	SER126
I	ASP127
I	THR153
I	ALA155
I	LEU156
I	ASP157
I	SER158
I	SER158
I	THR159
I	VAL161
I	GDP202

---

site_id	AF5
Number of Residues	14
Details	binding site for Ligand GLU I 162 bound to ASN I 160

Chain	Residue
I	ILE151
I	GLU152
I	THR153
I	THR159
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	ALA163
I	ALA163
I	ALA164
I	ALA164
I	PHE165
I	GLN166

---

site_id	AF6
Number of Residues	14
Details	binding site for Ligand GLU I 162 bound to ASN I 160

Chain	Residue
I	ILE151
I	GLU152
I	THR153
I	THR159
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	ALA163
I	ALA163
I	ALA164
I	ALA164
I	PHE165
I	GLN166

---

site_id	AF7
Number of Residues	14
Details	binding site for Ligand GLU I 162 bound to ASN I 160

Chain	Residue
I	ILE151
I	GLU152
I	THR153
I	THR159
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	ALA163
I	ALA163
I	ALA164
I	ALA164
I	PHE165
I	GLN166

---

site_id	AF8
Number of Residues	14
Details	binding site for Ligand GLU I 162 bound to ASN I 160

Chain	Residue
I	ILE151
I	GLU152
I	THR153
I	THR159
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	ALA163
I	ALA163
I	ALA164
I	ALA164
I	PHE165
I	GLN166

---

site_id	AF9
Number of Residues	14
Details	binding site for Ligand GLU I 162 bound to ASN I 160

Chain	Residue
I	ILE151
I	GLU152
I	THR153
I	THR159
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	ALA163
I	ALA163
I	ALA164
I	ALA164
I	PHE165
I	GLN166

---

site_id	AG1
Number of Residues	14
Details	binding site for Ligand GLU I 162 bound to ASN I 160

Chain	Residue
I	ILE151
I	GLU152
I	THR153
I	THR159
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	ALA163
I	ALA163
I	ALA164
I	ALA164
I	PHE165
I	GLN166

---

site_id	AG2
Number of Residues	14
Details	binding site for Ligand GLU I 162 bound to ASN I 160

Chain	Residue
I	ILE151
I	GLU152
I	THR153
I	THR159
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	ALA163
I	ALA163
I	ALA164
I	ALA164
I	PHE165
I	GLN166

---

site_id	AG3
Number of Residues	14
Details	binding site for Ligand GLU I 162 bound to ASN I 160

Chain	Residue
I	ILE151
I	GLU152
I	THR153
I	THR159
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	ALA163
I	ALA163
I	ALA164
I	ALA164
I	PHE165
I	GLN166

---

site_id	AG4
Number of Residues	28
Details	binding site for Di-peptide ARG I 30 and THR I 159

Chain	Residue
I	ASN26
I	LEU27
I	LEU28
I	SER29
I	SER29
I	PHE31
I	PHE31
I	THR32
I	THR32
I	ASN34
I	ASN34
I	GLU35
I	PHE36
I	THR153
I	SER154
I	SER154
I	ALA155
I	ALA155
I	LEU156
I	LEU156
I	ASP157
I	ASP157
I	SER158
I	SER158
I	ASN160
I	VAL161
I	VAL161
I	GLU162

---

site_id	AG5
Number of Residues	27
Details	binding site for Di-peptide ARG I 30 and ASP I 157

Chain	Residue
I	ASN26
I	ASN26
I	LEU27
I	LEU28
I	SER29
I	SER29
I	PHE31
I	PHE31
I	THR32
I	ARG33
I	ASN34
I	ASN34
I	GLU35
I	GLU35
I	PHE36
I	PHE36
I	ASP127
I	SER154
I	SER154
I	ALA155
I	ALA155
I	LEU156
I	LEU156
I	SER158
I	SER158
I	THR159
I	THR159

---

site_id	AG6
Number of Residues	28
Details	binding site for Di-peptide ARG I 30 and THR I 159

Chain	Residue
I	ASN26
I	LEU27
I	LEU28
I	SER29
I	SER29
I	PHE31
I	PHE31
I	THR32
I	THR32
I	ASN34
I	ASN34
I	GLU35
I	PHE36
I	THR153
I	SER154
I	SER154
I	ALA155
I	ALA155
I	LEU156
I	LEU156
I	ASP157
I	ASP157
I	SER158
I	SER158
I	ASN160
I	VAL161
I	VAL161
I	GLU162

---

site_id	AG7
Number of Residues	27
Details	binding site for Di-peptide ARG I 30 and ASP I 157

Chain	Residue
I	ASN26
I	ASN26
I	LEU27
I	LEU28
I	SER29
I	SER29
I	PHE31
I	PHE31
I	THR32
I	ARG33
I	ASN34
I	ASN34
I	GLU35
I	GLU35
I	PHE36
I	PHE36
I	ASP127
I	SER154
I	SER154
I	ALA155
I	ALA155
I	LEU156
I	LEU156
I	SER158
I	SER158
I	THR159
I	THR159

---

site_id	AG8
Number of Residues	21
Details	binding site for Di-peptide ARG I 30 and LEU I 156

Chain	Residue
I	ASN26
I	LEU27
I	LEU28
I	SER29
I	PHE31
I	THR32
I	ASN34
I	GLU35
I	GLU35
I	PHE36
I	PHE36
I	SER154
I	SER154
I	ALA155
I	ALA155
I	ASP157
I	ASP157
I	SER158
I	SER158
I	THR159
I	GDP202

---

site_id	AG9
Number of Residues	27
Details	binding site for Di-peptide ARG I 30 and ASP I 157

Chain	Residue
I	ASN26
I	ASN26
I	LEU27
I	LEU28
I	SER29
I	SER29
I	PHE31
I	PHE31
I	THR32
I	ARG33
I	ASN34
I	ASN34
I	GLU35
I	GLU35
I	PHE36
I	PHE36
I	ASP127
I	SER154
I	SER154
I	ALA155
I	ALA155
I	LEU156
I	LEU156
I	SER158
I	SER158
I	THR159
I	THR159

---

site_id	AH1
Number of Residues	21
Details	binding site for Di-peptide PHE I 31 and THR I 159

Chain	Residue
I	LEU27
I	LEU28
I	SER29
I	SER29
I	ARG30
I	ARG30
I	THR32
I	THR32
I	ARG33
I	ASN34
I	THR153
I	SER154
I	ASP157
I	ASP157
I	SER158
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	GLU162
I	PHE165

---

site_id	AH2
Number of Residues	21
Details	binding site for Di-peptide PHE I 31 and THR I 159

Chain	Residue
I	LEU27
I	LEU28
I	SER29
I	SER29
I	ARG30
I	ARG30
I	THR32
I	THR32
I	ARG33
I	ASN34
I	THR153
I	SER154
I	ASP157
I	ASP157
I	SER158
I	ASN160
I	ASN160
I	VAL161
I	VAL161
I	GLU162
I	PHE165

---

site_id	AH3
Number of Residues	22
Details	binding site for Di-peptide GLU I 35 and ASP I 157

Chain	Residue
I	ASN26
I	SER29
I	SER29
I	ARG30
I	ARG30
I	PHE31
I	ARG33
I	ARG33
I	ASN34
I	ASN34
I	PHE36
I	PHE36
I	ASP127
I	ASP127
I	SER154
I	SER154
I	ALA155
I	ALA155
I	LEU156
I	LEU156
I	SER158
I	THR159

---

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL

Chain	Residue	Details
A	VAL14-LEU27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	33
Details	Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	38
Details	Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15837192","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---