5JB2
Crystal structure of chicken LGP2 with 5'ppp 10-mer dsRNA and ADP-AlF4-Mg2+ at 2.2 A resolution.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002376 | biological_process | immune system process |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003724 | molecular_function | RNA helicase activity |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0045087 | biological_process | innate immune response |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 701 |
| Chain | Residue |
| A | CYS554 |
| A | CYS557 |
| A | CYS610 |
| A | CYS613 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue ADP A 702 |
| Chain | Residue |
| A | ALA28 |
| A | GLY29 |
| A | LYS30 |
| A | THR31 |
| A | ARG32 |
| A | GLU67 |
| A | ASP444 |
| A | ARG471 |
| A | ALF703 |
| A | MG704 |
| A | HOH804 |
| A | HOH828 |
| A | HOH869 |
| A | HOH934 |
| A | HOH935 |
| A | HOH999 |
| A | GLU2 |
| A | LEU3 |
| A | HIS4 |
| A | GLN7 |
| A | GLY27 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue ALF A 703 |
| Chain | Residue |
| A | THR26 |
| A | GLY27 |
| A | LYS30 |
| A | GLU132 |
| A | GLY442 |
| A | ARG469 |
| A | ARG471 |
| A | ADP702 |
| A | MG704 |
| A | HOH817 |
| A | HOH819 |
| A | HOH852 |
| A | HOH934 |
| A | HOH988 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 704 |
| Chain | Residue |
| A | ADP702 |
| A | ALF703 |
| A | HOH819 |
| A | HOH828 |
| A | HOH934 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG X 101 |
| Chain | Residue |
| A | HOH812 |
| X | GTP1 |
| X | G2 |
| X | HOH215 |
| X | HOH224 |
